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In this paper, we investigate a reinforcement learning of walking behavior for a four-legged robot. The robot has two servo motors per leg, so this problem has eight-dimensional continuous state/action space. We present an action selection scheme for actor-critic algorithms , in which the actor selects a continuous action from its bounded action space by(More)
In the present study, we attempted to explore cell transplantation therapy for intracerebral hemorrhage (ICH) using embryonic stem (ES) cells. Collagenase-induced ICH rats were used as model animals. Mouse ES cells were differentiated into nestin-positive neural stem cells in vitro by alltrans retinoic acid (ATRA). ATRA-treated ES cells (10(5)) were(More)
AIMS To investigate the efficacy of embryonic stem cell-derived neural stem cells (NSCs) for spinal cord injury (SCI) in mice and whether a combination treatment with thyroid hormone provides a more effective ES cell-based therapy. METHODS Nestin-positive NSCs were induced from undifferentiated mouse ES cells by a step-by-step culture and used as grafts.(More)
Proteomic profiling on Ecklonia cava Kjellman grown under various seawater temperatures was conducted to search for biomarkers that were useful to evaluate the health of the colonies and formulate actions for the maintenance of marine forests. In the cultivated strains, protein expression was not significantly changed when the cultivation temperature was(More)