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The Role of Rho GTPases in Toxicity of Clostridium difficile Toxins

• Shuyi Chen, Chunli Sun, Haiying Wang, Jufang Wang, Emmanuel Lemichez
• Toxins
• 2015

Clostridium difficile (C. difficile) is the main cause of antibiotic-associated diarrhea prevailing in hospital settings. In the past decade, the morbidity and mortality of C. difficile infection… (More)

Phaeosphaerins A-F, cytotoxic perylenequinones from an endolichenic fungus, Phaeosphaeria sp.

• Gang Li, Haiying Wang, +7 authors Hongxiang Lou
• Journal of natural products
• 2012

Six novel phototoxins, phaeosphaerins A-F, together with six known perylenequinones were isolated from an endolichenic fungus Phaeosphaeria sp. Their structures were determined unequivocally on the… (More)

Identification of an Essential Region for Translocation of Clostridium difficile Toxin B

• Shuyi Chen, Haiying Wang, +4 authors Jufang Wang
• Toxins
• 2016

Clostridium difficile toxin A (TcdA) and toxin B (TcdB) are the major virulence factors involved in C. difficile-associated diarrhea and pseudomembranous colitis. TcdA and TcdB both contain at least… (More)

Rapid detection of Clostridium difficile toxins and laboratory diagnosis of Clostridium difficile infections

• Shuyi Chen, Huawei Gu, Chunli Sun, Haiying Wang, Jufang Wang
• Infection
• 2016

Clostridium difficile is an anaerobic, spore-forming and Gram-positive bacillus. It is the major cause of antibiotic-associated diarrhea prevailing in hospital settings. The morbidity and mortality… (More)

Correction: Chen, S., et al. Identification of an Essential Region for Translocation of Clostridium difficile Toxin B. Toxins 2016, 8, 241

• Shuyi Chen, Haiying Wang, +4 authors Jufang Wang
• Toxins
• 2016

n/a.

Time-resolved transcriptome analysis of Clostridium difficile R20291 response to cysteine.

• Huawei Gu, Kan Shi, +6 authors Jufang Wang
• Microbiological research
• 2018

The incidence of Clostridium difficile infection has been steadily rising over the past decade. The increase in the rate of incidence is associated with the specific NAP1/BI/027 strains which are… (More)

Novel Cysteine Desulfidase CdsB Involved in Releasing Cysteine Repression of Toxin Synthesis in Clostridium difficile

• Huawei Gu, Yingyin Yang, +5 authors Jufang Wang
• Front. Cell. Infect. Microbiol.
• 2017

Clostridium difficile, a major cause of nosocomial diarrhea and pseudomembranous colitis, still poses serious health-care challenges. The expression of its two main virulence factors, TcdA and TcdB,… (More)

A Chimeric Vaccine Prevents Primary and Recurrent Clostridium difficile Infection

• Haiying Wang, Xiaoquan Sun, +8 authors Hanping Feng
• 2011

Tris(propane‐1,3‐diammonium) di‐μ5‐phosphato‐penta­molybdate(VI) tetra­hydrate

• Huiyan Liu, Haiying Wang, Feng Gao, Zaisheng Lu, Dezhong Niu
• 2006

Development of a fluorescent immnunochromatographic assay for the procalcitonin detection of clinical patients in China.

• Haiying Wang, Hong Wang, +4 authors Jufang Wang
• Clinica chimica acta; international journal of…
• 2015

BACKGROUND Procalcitonin (PCT) has been recognized as a biomarker in severe inflammation, infection and sepsis. PCT detection in serum requires sensitive and specific antibodies. In this study, we… (More)

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