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Csi1 links centromeres to the nuclear envelope for centromere clustering
Csi1 promotes centromere clustering by linking centromeres to the SUN domain protein Sad1 in the nuclear envelope.
Csi1 illuminates the mechanism and function of Rabl configuration
The nuclear envelope not only compartmentalizes the genome but is also home to the SUN-KASH domain proteins, which play essential roles both in genome organization and in linking the nucleus to the… Expand
Stretching, scrambling, piercing and entangling: Challenges for telomeres in mitotic and meiotic chromosome segregation.
- Haitong Hou, J. Cooper
- Medicine, Biology
- Differentiation; research in biological diversity
- 1 March 2018
The consequences of telomere loss or dysfunction become most prominent when cells enter the nuclear division stage of the cell cycle. At this climactic stage when chromosome segregation occurs,… Expand