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BACKGROUND AND OBJECTIVES The use of mesenchymal stem cells (MSC) for cell therapy relies on the capacity of these cells to home and engraft long-term into the appropriate target tissue(s). Homing of MSC to bone marrow (BM) post-transplantation can occur, but does so with only poor efficiency. This study was designed to evaluate the role of the SDF-1/CXCR4(More)
OBJECTIVES The aim of this study was to explore the profile and function of CD4(+)CD25(+) regulatory T cells (Treg cells) in idiopathic thrombocytopenic purpura (ITP) patients. METHODS Treg cell numbers were analyzed by flow cytometric analysis in peripheral blood mononuclear cells collected from healthy donors or patients with ITP. Quantification of cell(More)
OBJECTIVE To detect the quantity, proportion and function of producing cytokines of Th1 and Th2 cells in aplastic anemia (AA) patients and their contribution to the hematopoietic failure. METHODS (1) Eleven patients with severe aplastic anemia (SAA) at diagnosis were observed by Marsh's method for the CFU-E, BFU-E and CFU-GM before and after depletion of(More)
OBJECTIVE To examine the quantity and apoptosis-related protein level of B lymphocyte in the patients with immunorelated pancytopenia (IRP) and explore the role of B lymphocyte in the pathogenetic mechanism of IRP. METHODS Quantities of all B lymphocytes and CD(5)(+) B lymphocytes and the expressions of Fas and bcl-2 on B lymphocytes in 25 patients with(More)
OBJECTIVE To understand the clinical feature and natural course of polycythemia vera (PV). METHODS The clinical symptoms, signs, laboratory examination and prognosis of 185 patients with PV were analysed. RESULTS There are 122 males and 63 females. The mean age was (52.7 +/- 14.1) years. The mean hemoglobin level was (208.3 +/- 21.2) g/L. Pancytosis was(More)
A new algorithm based on information maximization is proposed, against the shortcomings of traditional Speech Blind separation of low convergence rate and high crosstalk error. It uses the new sign function to make mutual information of input and output to maximize by analyzing a variety of non-linear function of the separation performance. Experiments show(More)
CD70 and CD11a are co-stimulatory molecules that are important for the immune functions of T, B lymphocytes. Over-expressions of CD70 or CD11a cause T cell to be autoreactive. The purpose of this study was to explore the effect of CD70 and CD11a in immune thrombocytopenia (ITP). CD70 and CD11a mRNAs and protein expressions in CD4+ T cells from ITP patients(More)
A speech enhancement method based on wavelet packet transform and hearing masking effect is proposed. This method has following steps. Firstly, by perceptual wavelet packet the noisy speech is enhanced. Then by Johnston hearing masking model the noise hearing masking threshold is gained. Finally, by a perceptual filter based on hearing masking effect the(More)
If a transit vehicle breaks down on a schedule trip, there are some vehicles in the system need to serve this trip and the former plan must be changed. For solving the urgency vehicle routing problem with disruption that may be vehicle breakdowns or traffic accidents in the logistics distribution system, through the analysis of the problem and the(More)
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