Haiping Yao

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Poly(ADP-ribose)polymerase-1 (PARP-1) has emerged as a promising anticancer drug target due to its key role in the DNA repair process. In this work, a novel series of 1-benzyl-quinazoline-2,4(1H,3H)-dione derivatives were designed and synthesized as human PARP-1 inhibitors, structure-activity relationships were conducted and led to a number of potent PARP-1(More)
Sufficient intercommunication between ranging module and positioning module was lacked during the current research on the localization issue for IR-UWB wireless sensor networks. The idea of integrative ranging and positioning was proposed in this paper. The ranging module was designed to provide not only the range estimation results to the positioning(More)
The emerging theory of compressed sensing (CS) not only enables the reconstruction of sparse signals from a small set of random measurements, but also provides a universal signal demodulation approach at sub-Nyquist sampling rate. Compressed signal demodulation is particularly suitable for impulse ratio ultra-wideband (IR-UWB) communications where Nyquist(More)
Traditionally, high-precision TOA estimation for IR-UWB ranging relies on extremely high-rate sampling, which is difficult to implement with low-cost. In this paper, by introducing the newly emerging compressed sensing (CS) theory to the design of IR-UWB ranging system, low-rate sampling based high-precision TOA estimation is realized. The matching-pursuit(More)
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