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Artemisinins are the cornerstone of anti-malarial drugs. Emergence and spread of resistance to them raises risk of wiping out recent gains achieved in reducing worldwide malaria burden and threatens future malaria control and elimination on a global level. Genome-wide association studies (GWAS) have revealed parasite genetic loci associated with artemisinin(More)
The purpose of this study was to investigate the prevalence of human papillomavirus (HPV) genotypes infection in women with and with normal cervical histology in the littoral region of Shandong, China. Scrape specimens were collected from 4,601 women for Pap smear and HPV genotypes identification. 1,489 women without normal cytology or with cervical disease(More)
In this paper, we propose an adaptive synchronization control scheme to achieve both intra-stream and interstream synchronization for real-time streaming multimedia applications on the Internet. Based upon synchronization errors calculated in real-time, our scheme piecewisely adjusts the end-to-end delay to compensate for the delay variation. It does so by(More)
Oxidative dealkylation is a unique mechanistic pathway found in the alpha-ketoglutarate-Fe(II)-dependent AlkB family of enzymes to remove the alkylation damage to DNA bases and regenerate nucleobases to their native state. The B3LYP density functional combined with a self-consistent reaction field was used to explore the triplet, quintet, and septet(More)
In the context of drug discovery and development, much effort has been exerted to determine which conformers of a given molecule are responsible for the observed biological activity. In this work we aimed to predict bioactive conformers using a variant of supervised learning, named multiple-instance learning. A single molecule, treated as a bag of(More)
During the last few years the Internet has grown tremendously and has penetrated all aspects of everyday life. Starting off as a purely academic research network, the Internet is now extensively used for education, for entertainment, and as a very promising and dynamic marketplace, and is envisioned as evolving into a vehicle of true collaboration and a(More)
It is commonly believed that including domain knowledge in a prediction model is desirable. However, representing and incorporating domain information in the learning process is, in general, a challenging problem. In this research, we consider domain information encoded by discrete or categorical attributes. A discrete or categorical attribute provides a(More)
Best-effort packet switch networks such as the Internet can not guarantee in-time delivery of packetizzed data units for networked multimedia applications. For a video conferencing system, the original temporal relationships among data units could be severely distorted without appropriate control. In this paper, we propose an adaptive delay and(More)
The prevalence of the IEEE 802.11b technology leads to the emergence of Wi-Fi based AV conferencing applications. However, due to the "best-effort" transport service and other unpredictable factors such as user mobility, location and background traffic, the transport channel behavior often fluctuates drastically. It thus becomes rather difficult to(More)
Degradation of azo dye Acid Orange 7 (AO7) was investigated using zero-valent iron/granular activated carbon (Fe(0)/GAC) in the absence and presence of ultrasound (US). The AO7 degradation efficiency by Fe(0)/GAC was dramatically enhanced by ultrasound, ultrasound alone had a little effect on the degradation. Effects of Fe(0)/GAC ratios and initial pH(More)