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In order to develop an artificial intelligence and computer-aided diagnosis system that assists neuroradiologists to interpret magnetic resonance (MR) images. This paper employed Hu moment invariant (HMI) as the brain image features, and we proposed a novel predator-prey particle swarm optimization (PP-PSO) algorithm used to train the weights of(More)
BACKGROUND Glutathione S-transferases (GSTs) are a family of multifunctional enzymes that are involved in the metabolism of many xenobiotics, including a wide range of environmental carcinogens. While the null genotypes in GSTM1 and GSTT1 have been implicated in tumorigenesis, it remains inconsistent and inconclusive. Herein, we aimed to assess the possible(More)
PURPOSE We developed a computerized system for signal detection in spontaneous reporting system (SRS) of Shanghai. Data acquisition, data mining could be carried out automatically and the process of data preprocessing and cleaning could be facilitated. This system was expected to detect signals from SRS after drug licensing with minimum patient exposure. (More)
This paper aims to clarify the intrinsic limitations of electrochemical impedance spectroscopy (EIS) in measuring electric double layer (EDL) capacitance. For more than two decades, capacitances measured using EIS at low frequencies have been reported to be significantly smaller than those measured using other techniques without any definitive explanations.(More)
This paper presents a generalized modified Poisson−Nernst−Planck (MPNP) model derived from first principles based on excess chemical potential and Langmuir activity coefficient to simulate electric double-layer dynamics in asymmetric electrolytes. The model accounts simultaneously for (1) asymmetric electrolytes with (2) multiple ion species, (3) finite ion(More)
Lonicerae japonicae flos, a widely used traditional Chinese medicine (TCM), has been used for several thousand years in China. Chinese Pharmacopeia once included Lonicerae japonicae flos of Caprifoliaceae family and plants of the same species named Lonicerae flos in general in the same group. Chinese Pharmacopeia (2005 Edition) lists Lonicerae japonicae(More)
UNLABELLED WHAT IS ALREADY KNOWN ABOUT THE SUBJECT: * Concomitant use of different drugs may yield excessive risk for adverse drug reactions and it is a challenging task to do surveillance on the safety profile of the interaction between different drugs. * Currently, several methods are used by pharmacoepidemiologists and statisticians to detect possible(More)
PURPOSE To give an overview of the current status including problems and efforts about pharmacovigilance in Traditional Chinese Medicine (TCM) safety surveillance. METHODS It is based on literature review and publicly available data in China. RESULTS TCM led to several adverse drug reactions (ADRs) during the past few years and pharmacovigilance about(More)
In the past, scholars used various computer vision and artificial intelligence methods to detect brain diseases via magnetic resonance imaging (MRI). In this paper, we proposed a novel system to detect sensorineural hearing loss (SNHL). First, we used three-level bior4.4 wavelet to decompose original brain image. Second, principal component analysis (PCA)(More)