Learn More
T-cell receptor (TCR)-mediated cross-recognition is a major mechanism in the pathogenesis of drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome. However, the characteristics of the TCR repertoire and the clinical significance of repertoire reformation throughout the course of DRESS are unknown. Here, we isolated CD4(+) and CD8(+) T-cells(More)
25 A characteristic immunopathology of human cancers is the induction of tumor antigen-specific T 26 lymphocyte responses within solid tumor tissues. Current strategies for immune monitoring focus on the 27 quantification of the density and differentiation status of tumor-infiltrating T lymphocytes; however, 28 properties of the TCR repertoire ‒ including(More)
OBJECTIVE To study the changes in surface morphology of cobalt-chromium alloy, pure titanium and high-cobalt chromium molybdenum alloy immersed in artificial saliva with different concentrations of fluoride, and to analyze the corrosion resistance of these metals. METHODS The three kinds of metal were polished and then were immersed in artificial saliva(More)
Cyclin G1 protein is expressed in normal endometrial epithelial cells in a progesterone-dependent manner. It is an important mediator of the inhibiting effect of progesterone on cell proliferation. Moreover, the expression of cyclin G1 is also found to be decreased in human endometrial carcinoma cells (ECCs). To study the mechanism of decrease in the(More)
An interference method to remove all mosaic grating errors using a phase-difference reference window without compensation for coupled mosaic errors or analyzing the far-field diffraction intensity patterns is proposed. The reference window is achieved by adding a small-aperture prism; therefore, the incident light on the mosaic gratings contains two(More)
Cyclin G1 is the only cyclin that has either positive or negative effects on cell growth. Our previous study found decreased expression of cyclin G1 in human endometrial carcinoma tissues compared with normal endometrial tissues. The study aimed to evaluate cyclin G1 expression and its effect on proliferation of human endometrial carcinoma cells (ECCs).(More)
Industrialization and urbanization have led to increasingly serious levels of atmospheric heavy metal pollution, which is one of the main sources of heavy metals to terrestrial ecosystems. Therefore, it is essential to quantify atmospheric fluxes and explore their potential effects on natural ecosystems and human welfare. We monitored water-soluble heavy(More)
Phytoestrogen has previously been proposed as an alternative to hormone replacement therapy. Hispolon has been found to have phytoestrogenic properties. However, the possible effects of hispolon on estrogen receptors and other related molecules remain to be determined. This study was performed mainly to confirm the estrogenic function of hispolon as it(More)
Homeostatic maintenance of T cells with broad clonal diversity is influenced by both continuing output of young T cells from the thymus and ongoing turnover of preexisting clones in the periphery. In the absence of infection, self and commensal antigens are thought to play important roles in selection and homeostatic maintenance of the T-cell pool. Most(More)
A traditional double monochromatic measurement instrument of diffraction efficiency for a plane grating involves two major problems: one is the differences of output spectrum bandwidths during measurement of a standard reflection mirror and the tested grating; the other is overlapping of diffracted spectra, which influence testing accuracy of diffraction(More)
  • 1