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3-monochloropropane-1,2-diol does not cause neurotoxicity in vitro or neurobehavioral deficits in rats.
TLDR
It is demonstrated that no significant neurotoxic effects were present in 3-MCPD-treated rats compared to saline-treated control rats, whereas, acrylamide, used as a positive control, induced significant deficits in all neurobehavioral parameters in both male and female rats. Expand
Neurotoxicity Study of 1,3-Dichloro-2-Propanol in Rats
TLDR
It is demonstrated that no significant neurotoxic effects in vitro and in neurobehavior were observed in the 1,3-DCP-treated rats compared to saline-treated control rats, whereas, acrylamide induced significant increases of all neurobehavioral deficit parameters in both male and female rats. Expand