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Cerebral ischemia-reperfusion (I-R) is a complex pathological process. Although autophagy can be evoked by ischemia, its involvement in the reperfusion phase after ischemia and its contribution to the fate of neurons remains largely unknown. In the present investigation, we found that autophagy was activated in the reperfusion phase, as revealed in both(More)
Transient cerebral ischemia leads to endoplasmic reticulum (ER) stress. However, the contributions of ER stress to cerebral ischemia are not clear. To address this issue, the ER stress activators tunicamycin (TM) and thapsigargin (TG) were administered to transient middle cerebral artery occluded (tMCAO) mice and oxygen-glucose deprivation-reperfusion(More)
The role of the histamine H3 receptor (H3R) in cerebral ischaemia/reperfusion (I/R) injury remains unknown. Here we show that H3R expression is upregulated after I/R in two mouse models. H3R antagonists and H3R knockout attenuate I/R injury, which is reversed by an H3R-selective agonist. Interestingly, H1R and H2R antagonists, a histidine decarboxylase(More)
Phosphorus-modified tungsten nitride/reduced graphene oxide (P-WN/rGO) is designed as a high-efficient, low-cost electrocatalyst for the hydrogen evolution reaction (HER). WN (ca. 3 nm in size) on rGO is first synthesized by using the H3[PO4(W3O9)4] cluster as a W source. Followed by phosphorization, the particle size increase slightly to about 4 nm with a(More)
A low-cost catalyst for the hydrogen evolution reaction (HER) over a broad pH range is highly desired to meet the practical needs in different areas. In this study, hierarchical flower-like MoS2@MoP core-shell heterojunctions (HF-MoSP) are designed as a promising catalyst for HER over a broad pH range. The materials are obtained by the controllable(More)
Layer-like nanocarbons with high surface area and good conductivity are promising materials for supercapacitors due to their good ability for effective charge-transfer and mass-transfer. In this paper, stacked layer-like porous carbon containing RGO (reduced graphene oxides) (LPCG) was constructed via the GO-induced assembly of gelatin followed by(More)
Cluster-like molybdenum phosphide particles were anchored on reduced graphene oxide (MoP/rGO) with high uniformity by using phosphomolybdic acid as a molybdenum precursor based on a robust assembly-immobilization method. Benefiting from the small size, and even distribution of the MoP particles, the MoP/rGO hybrid exhibits superior electrocatalytic activity(More)
The anchoring of small-sized WN (tungsten nitride) nanoparticles (NPs) with good dispersion on carbon nanotubes (CNTs) offers an effective means of obtaining promising materials for use in electrocatalysis. Herein, an effective method based on grinding treatment followed by a nitridation process is proposed to realize this goal. In the synthesis, a solution(More)
The content of ESI Fig. S1 a) TEM and b) HRTEM image of LPCG-2-600; c) and d) is SAED from area 2 and area 1. Fig.S2. Nitrogen adsorption–desorption isotherm and pore size distribution (inset) of LPCG-2-600. Fig. S3. Nitrogen adsorption–desorption isotherm and pore size distribution (inset) of (a) RGO-600, (b) LPCG-1-600, (c) LPCG-3-600 and (d) PC-600. (c)(More)
In this study, sea-urchin shaped Bi2S3/CdS hierarchical heterostructures are successfully synthesized via a convenient one-pot growth rate controlled route. The product is mainly composed of Bi2S3 nanorods and CdS nanoparticles grown on their surfaces. The formation mechanism was proposed based on the evolution of morphology as a function of solvothermal(More)
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