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Allogenic lymphocyte immunotherapy (LIT) as a treatment for unexplained recurrent spontaneous abortion (URSA) is still controversial due to the lack of enough controls to evaluate its effectiveness. Eighteen randomized, placebo-controlled trials with LIT for URSA were included in the meta-analysis. Live birth rates for each group were extracted, and the(More)
STUDY HYPOTHESIS The transforming growth factor (TGF)-β/β-catenin pathway is involved in granulocytic myeloid-derived suppressor cell (G-MDSCs)-induced Foxp3 expression in CD4(+)CD25(-)T cells, which plays an essential role in maintaining feto-maternal tolerance. STUDY FINDING Decidual G-MDSCs play an important role in promoting Foxp3 induction in(More)
CONTEXT Identifying novel molecular markers for assessing endometrial receptivity is necessary for understanding human implantation and may help in improving the clinical outcome of in vitro fertilization. OBJECTIVE We aimed to compare the gene expression profiles of the pre-receptive vs receptive phases of the natural cycle in human endometrial biopsies.(More)
To investigate CXC chemokine receptor 2 (CXCR2)-mediated granulocytic myeloid-derived suppressor cells' (MDSCs) (G-MDSCs) functional characterization and their role in maternal-fetal interface. Proportions of CXCR2(+) MDSCs and CXCR2 protein levels in total MDSCs were lower in abortion-prone CBA/J×DBA/2 mice than in CBA/J×BALB/c mice with normal pregnancy.(More)
Pseudomonas aeruginosa, an important opportunistic pathogen, has a single polar flagellum which is an important virulence and colonization factor by providing swimming motility. This paper describes the functional characterization of a novel gene pfm (PA2950) of P. aeruginosa. The pfm encodes a protein that is similar to a number of short-chain alcohol(More)
This paper presents a novel approach for designing the portable wireless ECG monitoring terminal for use in mobile application in a personal healthcare scenario. For portable application purposes, an ultra-low power 16-bit micro controller acts as the core unit of the terminal. The ECG signal measurement module, storage module and Bluetooth wireless(More)
OBJECTIVES The purpose of this study was to evaluate differences in uterine artery blood flow parameters and pregnancy outcomes, if any. An investigation was conducted to determine the effects of low-dose aspirin on uterine artery blood flow indices in patients with recurrent pregnancy loss. METHODS This observational study included 353 Chinese women with(More)
In this paper, performance analysis of physical models and parameter optimization of two typical decoupling controllers are considered. Firstly, new relationship between velocity and acceleration for the nonlinear performance is established. Then, for the decoupled quasi-linearized system, the parameter region is optimized, in which the damping is bigger(More)
OBJECTIVE To establish a statistical model to predict thrombophilia in patients with unexplained recurrent pregnancy loss (URPL). METHODS A retrospective case-control study was conducted at Ren Ji Hospital, Shanghai, China, from March 2014 to October 2016. The levels of D-dimer (DD), fibrinogen degradation products (FDP), activated partial thromboplastin(More)