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Down-regulation of microRNA-200c is associated with drug resistance in human breast cancer
Drug resistance remains a major clinical obstacle to successful treatment in breast cancer patients, and the evidence of microRNAs involvement in cancer drug resistance has been emerging recently.… Expand
MicroRNAs and drug resistance of breast cancer: basic evidence and clinical applications
Breast cancer is the most common malignancy and leading cause of cancer mortality in women. Drug resistance is a major obstacle in systemic therapy of breast cancer, which leads therapeutic failure,… Expand
Estradiol induces HOTAIR levels via GPER-mediated miR-148a inhibition in breast cancer
HOTAIR plays an important role in the regulation of cancer cell proliferation and cancer invasion in breast cancer. The up-regulation of HOTAIR has been reported in both estrogen receptor (ER)… Expand
MiR-944 functions as a novel oncogene and regulates the chemoresistance in breast cancer
MircroRNAs are emerging as critical regulators in carcinogenesis and chemoresistance in multiple cancer types. In this study, we observed that the miR-944 level was upregulated in breast cancer… Expand
Solid-pseudopapillary neoplasms of the pancreas: clinical and pathological features of 33 cases
PurposeSolid-pseudopapillary neoplasms (SPNs) are rare pancreatic tumors, with a low potential for malignancy. The clinical and pathological features of 33 SPNs were reviewed.MethodsThis study… Expand
Honokiol synergizes chemotherapy drugs in multidrug resistant breast cancer cells via enhanced apoptosis and additional programmed necrotic death.
- W. Tian, Y. Deng, L. Li, Haifei He, J. Sun, Dong Xu
- Medicine, Biology
- International journal of oncology
- 1 February 2013
Multidrug resistance (MDR) is a major challenge in cancer therapy. Apoptosis tolerance is one of the key mechanisms of MDR. Honokiol, a small-molecule pharmacologically active component, exhibits… Expand
Diaphragmatic perforation with colonic herniation due to hepatic radiofrequency ablation: A case report and review of the literature
Radiofrequency ablation (RFA) has been widely accepted as an alternative treatment for unresectable primary and metastatic hepatic tumors, with satisfactory rates of local response and significant… Expand
New clinical application of high-intensity focused ultrasound: local control of synovial sarcoma
High-intensity focused ultrasound (HIFU) is playing an increasingly important role in cancer therapy. Primary synovial sarcomas of the chest wall are extremely rare. We report the first case of… Expand
GPER mediated estradiol reduces miR-148a to promote HLA-G expression in breast cancer.
- Sifeng Tao, Haifei He, Q. Chen, Wenjie Yue
- Medicine, Biology
- Biochemical and biophysical research…
- 15 August 2014
Breast cancer is the most common malignant diseases in women. miR-148a plays an important role in regulation of cancer cell proliferation and cancer invasion and down-regulation of miR-148a has been… Expand
MicroRNA-101 sensitizes hepatocellular carcinoma cells to doxorubicin-induced apoptosis via targeting Mcl-1.
- Haifei He, W. Tian, Hai-Long Chen, Yongchuan Deng
- Biology, Medicine
- Molecular medicine reports
- 1 February 2016
MicroRNAs (miRNAs/miRs) are important regulators of multiple cellular processes, and their dysregulation is a common event in tumorigenesis, including the development of hepatocellular carcinoma… Expand