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Protein phosphorylation catalyzed by kinases plays essential roles in various intracellular processes. With an increasing number of phosphorylation sites verified experimentally by high-throughput technologies and assigned as substrates of specific kinases, prediction of potential kinase-substrate relations (KSRs) attracts increasing attention. Although a… (More)
By using the critical point theory of variational approach and Lax-Milgram theorem, we obtain the new results for the existence of the solution of the second-order impulsive elliptic differential equations with periodic boundary value problems.