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BACKGROUND CD8+ T cells participate in airway hyperresponsiveness (AHR) and allergic pulmonary inflammation that are characteristics of asthma. CXCL10 by binding to CXCR3 expressed preferentially on activated CD8+ T cells, attracts T cells homing to the lung. We studied the contribution and limitation of CXCR3 to AHR and airway inflammation induced by(More)
Traveling salesman problem is widely utilized as the typical issue for algorithm performance research because of its important engineering and theoretical value. An adaptive Markov Chain Monte Carlo algorithm is employed in resolving TSP for the purpose of ameliorating the temperature management problems in the original Metropolis algorithm. In order to get(More)
A generalization of the Novikov equation is investigated. Applying the limit of viscous approximations for the equation, we establish its existence of global weak solutions in the space C([0, ∞) × R) ∩ L ∞ ([0, ∞); H 1 (R)) under certain conditions. Our analysis depends on that we derive a one-sided super bound and a higher-norm estimate on the first order(More)
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