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BACKGROUND Mimecan plays an important role in endothelial and vascular smooth muscle cell integrity and may be involved the pathology of arterial stiffness. However, the role of mimecan in arterial stiffness in patients with hypertension is not well defined. METHODS AND RESULTS A total of 116 hypertension patients and 54 healthy controls were enrolled in(More)
Semaphorin 4D (Sema4D/CD100) is a 150-kDa transmembrane glycoprotein expressed by platelets and T-cells. When these cells are activated, Sema4D is cleaved proteolytically, generating a biologically active 120-kDa fragment (soluble Sema4D) capable of targeting receptors on platelets, B-cells, endothelial cells and tumor cells. However, its plasma levels and(More)
Adropin is a recently identified bioactive protein that promotes energy homeostasis by affecting glucose and lipid metabolism. Recently, adropin has also been reported to be associated with endothelial dysfunction. Also, ET-1, as a biomarker for endothelial dysfunction, is a key regulator in hypertension. Accordingly, the aim of the present study was to(More)
The paper is concerned with existence of mild solution of evolution equation with Hilfer fractional derivative which generalized the famous Riemann–Liouville fractional derivative. By noncompact measure method, we obtain some sufficient conditions to ensure the existence of mild solution. Our results are new and more general to known results. Nowadays,(More)
Objective: To investigate the clinical value of combined detection of plasma D-Dimer and fibrinogen degradation products (FDP) on predicting the prognosis of patients with acute coronary syndrome (ACS). Methods: 126 patients confirmed of ACS at our hospital were selected in this study, and divided into two groups-observation group (68 cases, with MACE) and(More)
This paper mainly tends to utilize [Formula: see text]-type function to investigate p-th moment and almost sure stability for a class of stochastic switched nonlinear systems. Based on the multiple Lyapunov functions approach, some sufficient conditions are derived to check the stability criteria of stochastic switched nonlinear systems. One numerical(More)
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