Hai-yun Li

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Soluble oligomers of amyloid-β peptide (Aβ) are emerging as the primary neurotoxic species in Alzheimer disease, however, whether the membrane is among their direct targets that mediate the downstream adverse effects remains elusive. Herein, we show that multiple soluble oligomeric Aβ preparations, including Aβ-derived diffusible ligand, protofibril, and(More)
BACKGROUND To compare different reference images selected for registration among chemical exchange saturation transfer (CEST) series. MATERIALS AND METHODS Five normal volunteers and eight brain tumor patients were studied on a 3 Tesla scanner. Image registration was performed by choosing each of the acquired CEST saturation or unsaturation dynamic images(More)
Tegument antigens of tapeworm play an important role in modulation of host response and parasite survival. Characterizing appropriate antigens for parasite infection diagnosis and vaccination is rational and could have both economic and epidemiological significance in poultry industry. In the present study, a major protoscolex homologue (named RT10) of(More)
Image registration between planning CT images and cone beam-CT (CBCT) images is one of the key technologies of image guided radiotherapy (IGRT). Current image registration methods fall roughly into two categories: geometric features-based and image grayscale-based. Mutual information (MI) based registration, which belongs to the latter category, has been(More)
This paper presents a new functional image fusion algorithm which is the combination of SPM and ICA using multi-resolution decomposition. Firstly, we designed the fMRI experiments and obtained the fMRI image data from different experimental conditions. The brain activated regions were extracted by the SPM and ICA methods respectively. Secondly, by(More)
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