Hai-cheng Wang

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Keratocystic odontogenic tumors (KCOT) are benign, locally aggressive intraosseous tumors of odontogenic origin. KCOT have a higher stromal microvessel density (MVD) than dentigerous cysts (DC) and normal oral mucosa. To identify genes in the stroma of KCOT involved in tumor development and progression, RNA sequencing (RNA-Seq) was performed using samples(More)
OBJECTIVE In the current study, we aimed to investigate the effects of alveolar decortication on local bone remodeling, and to explore the possible mechanism by which decortication facilitates tooth movement. MATERIALS AND METHODS Forty rabbits were included in the experiment. The left mandible was subjected to decortication-facilitated orthodontics, and(More)
BACKGROUND & OBJECTIVE Signal cascades of mitogen-actived protein kinase(MAPK) and signal transducer and activator of transcription 3 (Stat3) are two main signal transduction pathways which were associated with cell proliferation and malignant transformation.MAPK and Stat3 proteins are activated by phosphorylation. The biological effects which are caused by(More)
OBJECTIVE To investigate the expression of proliferating cell nucleus antigen (PCNA) and nm23 protein in hepatocellular carcinoma (HCC) and their relation with metastasis. METHODS The expression of PCNA and nm23 protein in 56 HCCs were detected by the immunohistochemical technique. RESULTS Of the 56 HCCs, the expression strength of PCNA and nm23 protein(More)
Cancer cell-derived immunoglobulin G (cancer-IgG) has been implicated in the pathogenesis and progression of various types of cancer. However, its role in salivary adenoid cystic carcinoma (SACC) remains unclear. The present study aimed to investigate the effects of cancer-IgG on metastasis and prognosis in 96 patients with SACC. Immunohistochemical(More)
OBJECTIVE Cancer-IgG is a newly-discovered molecule, mainly derived from epithelial carcinoma cells and is significantly correlated with differentiation, metastasis, local invasion, and poor prognosis of many cancers. In our previous study we detected IgG expression in oral epithelial carcinoma, including salivary adenoid cystic carcinoma (SACC), using an(More)
OBJECTIVE To observe the protective effect on renal function of Chinese drugs combined with benazepril in patients with diabetic nephropathy (DN). METHODS Adopting stratified randomized and controlled design, 108 patients with DN were assigned to two groups. Besides the same measures of diet regulation, exercise, education, hypoglycemic and symptomatic(More)
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