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We consider all 1/2 BPS excitations of AdS × S configurations in both type IIB string theory and M-theory. In the dual field theories these excitations are described by free fermions. Configurations which are dual to arbitrary droplets of free fermions in phase space correspond to smooth geometries with no horizons. In fact, the ten dimensional geometry(More)
We study theories with sixteen supercharges and a discrete energy spectrum. One class of theories has symmetry group SU (2|4). They arise as truncations of N = 4 super Yang Mills. They include the plane wave matrix model, 2+1 super Yang Mills on R × S 2 and N = 4 super Yang Mills on R × S 3 /Z k. We explain how to obtain their gravity duals in a unified(More)
Hemichannels in the overlapping regions of apposing cells plasma membranes join to form gap junctions and provide an intercellular communication pathway. Hemichannels are also present in the non-junctional regions of individual cells and their activity is gated by several agents, including calcium. However, their physiological roles are unknown. Using(More)
Micro-indels (insertions or deletions shorter than 21 bps) constitute the second most frequent class of human gene mutation after single nucleotide variants. Despite the relative abundance of non-frameshifting indels, their damaging effect on protein structure and function has gone largely unstudied. We have developed a support vector machine-based method(More)
Blind motion deblurring estimates a sharp image from a motion blurred image without the knowledge of the blur kernel. Although significant progress has been made on tackling this problem, existing methods, when applied to highly diverse natural images, are still far from stable. This paper focuses on the robustness of blind motion deblurring methods toward(More)
We study instanton solutions and superpotentials for the large number of vacua of the plane-wave matrix model and a 2+1 dimensional Super Yang-Mills theory on R × S 2 with sixteen supercharges. We get the superpotential in the weak coupling limit from the gauge theory description. We study the gravity description of these instantons. Perturbatively with(More)
Genetic risk factors for intracranial aneurysm (IA) are not yet fully understood. Genomewide association studies have been successful at identifying common variants; however, the role of rare variation in IA susceptibility has not been fully explored. In this study, we report the use of whole exome sequencing (WES) in seven densely-affected families (45(More)
Alzheimer's disease (AD) is a protein misfolding disease. Early hypothesis of AD pathology posits that 39-43 AA long misfolded amyloid beta (Abeta) peptide forms a fibrillar structure and induces pathophysiological response by destabilizing cellular ionic homeostasis. Loss of cell ionic homeostasis is believed to be either indirectly due to amyloid(More)