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Secovironolide, a Novel Furanosteroid Scaffold with a Five-Membered B Ring from the Endophytic Fungus Talaromyces wortmannii LGT-4.
Two novel compounds, secovironolide (I) and epoxyvirone (II), together with five known viridian derivatives are isolated from the title fungus.
Secovironolide, a novel furanosteroid scaffold with a five-membered B ring from the endophytic fungus Talaromyces wortmannii LGT-4
Secovironolide (1) was purified from the culture broth of Talaromyces wortmanni and is the first example of a furanosteroid scaffold bearing a five-membered B ring. The structure of 1 was elucidated… Expand