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We have acknowledged with great attention the recent article of Leclerc et al. reporting a synergistic cytotoxicity of methotrexate (MTX) and histone deacetylase inhibitors (HDACis) combination(More)
PURPOSE Approximately 20% of children with acute lymphoblastic leukemia (ALL) suffer a relapse, and their prognosis is unfavorable. Between 1987 and 1990, the multicenter trial Acute Lymphoblastic(More)