Hae-Won Lee

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Death receptors (DRs) can induce apoptosis by oligomerization with TRAIL, whereas death decoy receptors (DcRs) cannot, due to their lack of functional intracellular death domains. However, it is not known whether DRs and DcRs can interact with one another to form oligomeric complexes prior to TRAIL binding. To address this issue, the extracellular domains(More)
A novel, red-pigmented, pleomorphic and short rod-shaped haloarchaeon, designated B8T, was isolated from a salt-fermented seafood. Strain B8T was found to be able to grow at 20–45 °C, in the presence of 15–30 % (w/v) NaCl and at pH 7.0–9.0. The optimum requirements were found to be a temperature range of 35–40 °C, pH 8.0 and the presence of 25 % NaCl. The(More)
Lymphocytes from eight individuals out of 60 healthy donors, whose plasmas showed relatively higher antibody titer for a target antigen of death receptor 5 (DR5), were selected for the source of antibody genes to construct so called an anti-DR5 pseudo-immune human single-chain fragment variable (scFv) library on the yeast cell surface (approximately 2x10(6)(More)
Two Gram-stain negative, rod-shaped and motile extreme halophiles, designated CBA1107T and CBA1108, were isolated from non-purified solar salt. Based on the phylogenetic analysis, strains CBA1107T and CBA1108 were shown to belong to the genus Halolamina, with similarities for the 16S rRNA gene sequences between strains CBA1107T and Halolamina pelagica(More)
A halophilic archaeal strain, designated CBA1105T, was isolated from non-purified solar salt. Strain CBA1105T was found to have three 16S rRNA genes, rrnA, rrnB and rrnC; similarities between the 16S rRNA gene sequences were 99.5–99.7 %. The phylogenetic analysis of the 16S rRNA gene sequences showed that strain CBA1105T forms a distinct clade with the(More)
A novel, red-pigmented and coccoid haloarchaeon, designated strain CBA1101T, was isolated from a marine sediment. Phylogenetic analysis based on 16S rRNA gene sequences indicated that strain CBA1101T is most closely related to the genus Halococcus in the family Halobacteriaceae. Strain CBA1101T had a highest 16S rRNA gene sequence similarity of 98.4 % with(More)
A Gram-negative, nonmotile, endospore-forming, rod-shaped bacterial strain LHW35T, which belonged to the genus Paenibacillus, was isolated from marine sediment collected from the south coast of the Republic of Korea. A phylogenetic analysis of 16S rRNA gene sequences indicated that strain LHW35T was most closely related to Paenibacillus taiwanensis(More)
A novel, strictly anaerobic, moderately thermophilic, endospore-forming, sulfate-reducing bacterium, designated TGB60-1T, was isolated from a hydrothermal sediment vent collected from the Tofua Arc in the Tonga Trench. The strain was characterized phenotypically and phylogenetically. The isolated strain was observed to be Gram-positive, with slightly curved(More)
A halophilic archaeon, designed strain CBA1103T, was isolated from non-purified solar salt. The cells of strain CBA1103T were observed to be Gram-stain negative and pleomorphic, and the colonies appear red. Strain CBA1103T was observed to grow between 20 and 55 °C (optimum 37 °C), and in NaCl concentrations of 10–30 % (w/v) (optimum 15 %) with 0–0.5 M(More)
An extremely halophilic archaeon, Haladaptatus cibarius D43(T), was isolated from traditional Korean salt-rich fermented seafood. Strain D43(T) shows the highest 16S rRNA gene sequence similarity (98.7 %) with Haladaptatus litoreus RO1-28(T), is Gram-negative staining, motile, and extremely halophilic. Despite potential industrial applications of extremely(More)