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PURPOSE OF REVIEW There is an increasing interest and availability of micro-invasive glaucoma surgery (MIGS) procedures. It is important that this increase is supported by sound, peer-reviewed evidence. This article will define MIGS, review relevant publications in the period of annual review and discuss future directions. RECENT FINDINGS The results of(More)
PURPOSE To examine outcomes through 36 months in phakic eyes with newly diagnosed primary open-angle glaucoma (POAG) naïve to therapy randomized to treatment with two trabecular micro-bypass stents or topical prostaglandin. METHODS Subjects with POAG naïve to therapy, with intraocular pressure (IOP) ≥21 and ≤40 mmHg, were randomized to implantation of two(More)
PURPOSE To compare the outcomes of combined cataract surgery with trabecular microbypass stents and ab interno trabeculotomy in patients with open-angle glaucoma. SETTING University of Toronto, Toronto, Ontario, and University of Montreal, Montreal, Quebec, Canada, and Glaucoma Associates of Texas, Dallas, Texas, USA. DESIGN Retrospective case series.(More)
The first line of the section ‘‘Subject Accountability, Demographics, and Pre-Study Parameters’’ under Results was incorrectly published. The correct sentence should read: ‘‘A total of 101 subjects completed the screening examination and were randomized to treatment with either two stents or with travoprost.’’ Open Access. This article is distributed under(More)
PURPOSE To describe the incidence and outcomes of reoperations for glaucoma in the Tube Versus Trabeculectomy (TVT) Study. DESIGN Cohort study of patients in a multicenter randomized clinical trial. METHODS The TVT Study enrolled 212 patients with medically uncontrolled glaucoma who had previous cataract and/or glaucoma surgery. Randomization assigned(More)
A 26-year-old woman presented with signs and symptoms of acute angle-closure glaucoma (ACG) in her left eye. Extended-depth spectral-domain optical coherence tomography (SD-OCT) was performed to biometrically assess the anterior chamber depth and crystalline lens conformation. Extended-depth SD-OCT imaging of the crystalline lens showed bilateral(More)
This study evaluates the morphologic effect of the implantation of two different sizes of the Hydrus microstent on the outer wall of Schlemm's canal (SC) and collector channel (CC) ostia. Twelve human eyes were dissected at the equator removing the iris, lens, ciliary body and vitreous. The cornea was excised with a corneal trephine exposing a direct view(More)
PURPOSE To assess the biocompatibility of a novel implant made of Nitinol (nickel-titanium alloy), designed to improve aqueous humor outflow. MATERIALS AND METHODS In the first arm of biocompatibility testing, microstents were surgically inserted into Schlemm's canal (SC) of 2 non-human primates (NHPs), and a third NHP served as a surgical sham control.(More)