Hadrien A. Clarke

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One mechanism by which viral tropism may be controlled is by the expression of a specific virus receptor on the cell surface. This paper reports the identification of a putative cellular receptor for visna virus, the prototype virus of the family Lentiviridae. Using a virus overlay protein blot assay we identified a group of polypeptides of apparent Mr 30K(More)
Although indirect evidence suggests that the control of sympathetic preganglionic neurons is mediated to a great extent through interneurons, little is known about the location, morphology or neurotransmitter phenotype of such interneurons. This limitation seriously impedes our understanding of spinal synaptic circuits crucial to control of arterial(More)
Basic block vectorization consists in extracting instruction level parallelism inside basic blocks in order to generate SIMD instructions and thus speedup data processing. It is however a double-edged technique, because the vectorized program may actually be slower than the original one. Therefore, it would be useful to predict beforehand whether or not(More)
We introduce MAD7, a tool that rapidly simulates many-core memory architectures at a functional level. MAD7 focuses on tracking access patterns and data spatial localities rather than enforcing any precise on-chip arbitration protocols. Although not cycle accurate by nature, it provides useful insights when comparing different memory architectures under(More)
Shorter interconnects and higher integration are among the benefits that 3D die-stacking is expected to bring to future integrated circuits. However, when stacking power-dissipating dies one on top of the other, the total power density increases accordingly. As a result, temperatures in 3DICs are exacerbated. TSVs are regarded as a solution since they are(More)
This paper introduces PASTIS, a novel photonic arbitration protocol based on a scalable token injection scheme, and ring-based nanophotonic technology. It aims at connecting together processors and memories in many-core computer systems by means of a ring topology. The main strength of PASTIS lays in the fact that it uses photonic components exclusively,(More)
Increasing the number of processing cores on chip multiprocessors has become a mainstream strategy to boost their capabilities. At the same time, there is a need for tools to help design on-chip memory architectures supporting these newly added cores. Such tools are usually fully implemented in software which are unfortunately difficult to scale, partly(More)
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