Hadi Karimzadeh

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We presented a 34-year-old woman with blurred vision and inability to walk due to acute optic neuritis and transverse myelitis, neuromyelitis optica (Devic’s syndrome), for an interesting presentation of this syndrome with proteinuria as the first manifestation of systemic lupus erythematosus.
BACKGROUND Antinuclear antibodies (ANAs) in women with recurrent miscarriage have been reported. The presence of moderate to high titers of these antibodies represents an autoimmune condition that can endanger the health of the fetus in pregnant women. OBJECTIVE In this study, we evaluated the prevalence of ANAs in Iranian women with a history of two or(More)
BACKGROUND The role of obesity in clinical curse of rheumatoid arthritis (RA) is not clear. We investigated the association of obesity and adiposity with disease activity and clinical response to combination therapy in RA patients. MATERIALS AND METHODS Active RA patients with the disease activity score using 28 joint counts (DAS28) > 2.6 were studied.(More)
In a previous study, we observed immunoprophylaxis failure due to occult hepatitis B virus (HBV) infection (OBI) despite the presence of adequate levels of anti-HBs in 21 (28%) of 75 children born to HBsAg-positive mothers. The aim of the study was to explore the maintenance of this cryptic condition in this population. Of 21 OBI-positive children, 17 were(More)
BACKGROUND HLA-B*27 is strongly associated with ankylosing spondylitis (AS). It represents a family of alleles that differ among ethnic groups. OBJECTIVE The aim of this study was to determine the distribution of HLA-B*27 alleles in AS patients and healthy controls in Isfahan (Iran). METHODS Sixty AS patients and 430 healthy blood donors were selected.(More)
OBJECTIVES There is some controversy regarding the effect of opium addiction on the coronary artery disease (CAD). The aim of this study was to determine the association between chronic opium consumption and CAD. METHODS This study had a case-control design. The patients recruited to the study were selected from angiography files in Department of(More)
Osteonecrosis of bone is a major cause of morbidity in lupus patients, and is most common in the femoral head. It has been reported in wide range of patients (2–30%). In different studies presence of arthritis, Raynaud phenomenon, vasculitis, pleuritis, antiphospholipid and other factors were associated with this occurrence. Bone infarcts were also(More)
INTRODUCTION This study was conducted to evaluate the survival of patients with lupus nephritis (LN) in two different lupus clinics in Iran. METHODS This was a retrospective cohort study covering 82 patients diagnosed with biopsy-proven LN hospitalized between 1994 until 2010. Demographic, clinical, laboratory, therapeutic and end-point data were(More)
BACKGROUND Immunomodulators and Nucleotide analogues have been used globally for the dealing of chronic hepatitis B virus (HBV) infection. However, the development of drug resistance is a major limitation to their long-term effectiveness. OBJECTIVES The aim of this study was to characterize the hepatitis B virus reverse transcriptase (RT) protein(More)
  • A Khedive, M Norouzi, +27 authors S M Jazayeri
  • Journal of viral hepatitis
  • 2013
Mutations within the coding region of hepatitis B surface antigen (HBsAg) have been found naturally in chronic carriers. To characterize the mutations of HBsAg from Iranian chronic carriers who were vaccine and/or medication naive. The surface genes from 360 patients were amplified and directly sequenced. The distribution of amino acid substitutions was(More)