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Healthcare outcomes assessed with observational study designs compared with those assessed in randomized trials.

TLDR
A systematic analysis of study design features, risk of bias, parameter interpretation, and effect size for all types of randomized and non-experimental observational studies is needed to identify specific differences in design types and potential biases.
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Effectiveness of semen washing to prevent human immunodeficiency virus (HIV) transmission and assist pregnancy in HIV-discordant couples: a systematic review and meta-analysis.

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Antiretroviral interventions for preventing breast milk transmission of HIV.

TLDR
To determine which antiretroviral prophylactic regimens are efficacious and safe for reducing mother-to-child transmission of HIV through breastfeeding and thereby avert child morbidity and mortality, a review of Randomized controlled trials from January 1, 1994 to January 14, 2014 identified relevant studies.
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Effectiveness of School-Based Teen Pregnancy Prevention Programs in the USA: a Systematic Review and Meta-Analysis

TLDR
Identified evidence indicated no consistent difference in rates of pregnancies between intervention recipients and controls, and the quality of evidence was low or very low.
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Do School-Based Programs Prevent HIV and Other Sexually Transmitted Infections in Adolescents? A Systematic Review and Meta-analysis

TLDR
The most effective intervention spanned 6 years, was a social development-based intervention with multiple components, rather than a sex education program, and started in first grade, thus offering no persuasive evidence for the effectiveness of school-based programs.
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Interventions for treating patients with chikungunya virus infection-related rheumatic and musculoskeletal disorders: A systematic review

TLDR
Results from these small trials provide insufficient evidence to draw conclusions about the efficacy or safety of CHIKV interventions, and Rigorous trials with sufficient statistical power are urgently needed.
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Reducing the global burden of Preterm Birth through knowledge transfer and exchange: a research agenda for engaging effectively with policymakers

TLDR
A research agenda for promoting KTE with policymakers is proposed, with an ambitious but realistic goal of reducing the global burden of PTB.
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Care Cascade for targeted tuberculosis testing and linkage to Care in Homeless Populations in the United States: a meta-analysis

TLDR
Targeted TB testing of persons experiencing homelessness appears effective in detecting LTBI and connecting persons to care and potential treatment, and costs of testing and treatment.
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Training for Better Management: Avante Zambézia, PEPFAR and Improving the Quality of Administrative Services Comment on "Implementation of a Health Management Mentoring Program: Year-1 Evaluation of…

TLDR
This work discusses other examples of successful administrative training programs that vary in the proportion of time that is spent learning on the job and theportion of time spent in classrooms and suggests that these programs should be more rigorously evaluated.
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Supportive interventions to improve retention on ART in people with HIV in low- and middle-income countries: A systematic review

TLDR
Supportive interventions are associated with increased ART programme retention, but evidence quality is generally low to moderate, suggesting that programmes addressing psychosocial needs can significantly help retain patients in care.
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