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The recent introduction of high-resolution molecular imaging technology is considered by many experts as a major breakthrough that will potentially lead to a revolutionary paradigm shift in health care and revolutionize clinical practice. This paper intends to balance the capabilities of the two major molecular imaging modalities used in nuclear medicine,(More)
Historically, anatomical CT and MR images were used to delineate the gross tumour volumes (GTVs) for radiotherapy treatment planning. The capabilities offered by modern radiation therapy units and the widespread availability of combined PET/CT scanners stimulated the development of biological PET imaging-guided radiation therapy treatment planning with the(More)
Photon attenuation in tissues is the primary physical degrading factor limiting both visual qualitative interpretation and quantitative analysis capabilities of reconstructed Positron Emission Tomography (PET) images. This study investigates the implementation and applicability of transmission atlas-guided attenuation correction in cerebral 3D PET imaging,(More)
This paper deals with the flow dynamics around a competitive swimmer during underwater glide phases occurring at the start and at every turn. The influence of the head position, namely lifted up, aligned and lowered, on the wall shear stress and the static pressure distributions is analyzed. The problem is considered as 3D and in steady hydrodynamic state.(More)
It has recently been shown that the attenuation map can be estimated from time-of-flight (TOF) PET emission data using joint maximum likelihood reconstruction of attenuation and activity (MLAA). In this work, we propose a novel MRI-guided MLAA algorithm for emission-based attenuation correction in whole-body PET/MR imaging. The algorithm imposes MR spatial(More)
— Medical volume segmentation is an essential stage in volume processing. This stage is important for tumour classification and quantification in medical volumes particularly in positron emission tomography (PET) imaging. Analysing PET volumes at early stage of illness is important for radiotherapy planning, tumour diagnosis, and fast recovery. There are(More)
Reliable attenuation correction methods for quantitative emission CT (ECT) require accurate delineation of the body contour and often necessitate knowledge of internal anatomic structure. Two broad classes of methods have been used to calculate the attenuation map: transmission-less and transmission-based attenuation correction techniques. Whereas(More)
Magnetic resonance imaging (MRI)-guided partial volume effect correction (PVC) in brain positron emission tomography (PET) is now a well-established approach to compensate the large bias in the estimate of regional radioactivity concentration, especially for small structures. The accuracy of the algorithms developed so far is, however, largely dependent on(More)