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  • Ping Yu, Randal K. Gregg, +9 authors Habib Zaghouani
  • Biology, Medicine
  • Journal of immunology
  • 2005 (First Publication: 1 June 2005)
  • To date, very few Ag-based regimens have been defined that could expand T regulatory (Treg) cells to reverse autoimmunity. Additional understanding of Treg function with respect to specificity andContinue Reading
  • Renu G. Jain, Danielle M. Tartar, +8 authors Habib Zaghouani
  • Medicine
  • The Journal of experimental medicine
  • 2008 (First Publication: 21 January 2008)
  • The role of Th17 cells in type I diabetes (TID) remains largely unknown. Glutamic acid decarboxylase (GAD) sequence 206-220 (designated GAD2) represents a late-stage epitope, but GAD2-specific T cellContinue Reading
  • Hyun-Hee Lee, Christine M. Hoeman, +7 authors Habib Zaghouani
  • Biology, Medicine
  • The Journal of experimental medicine
  • 2008 (First Publication: 29 September 2008)
  • Primary neonatal T cell responses comprise both T helper (Th) cell subsets, but Th1 cells express high levels of interleukin 13 receptor alpha1 (IL-13R alpha 1), which heterodimerizes with IL-4RContinue Reading
  • Randal K. Gregg, Renu G. Jain, +5 authors Habib Zaghouani
  • Biology, Medicine
  • Journal of immunology
  • 2004 (First Publication: 15 December 2004)
  • Autoimmunity presumably manifests as a consequence of a shortfall in the maintenance of peripheral tolerance by CD4(+)CD25(+) T regulatory cells (Tregs). However, the mechanism underlying theContinue Reading