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Substrate specificity of a galactose 6-phosphate isomerase from Lactococcus lactis that produces d-allose from d-psicose.
The recombinant galactose 6-phosphate isomerase (LacAB) from Lactococcus lactis was purified using HiTrap Q HP and Phenyl-Sepharose columns and had broad specificity for various aldoses and ketoses. Expand
Theaflavins enhance intestinal barrier of Caco-2 Cell monolayers through the expression of AMP-activated protein kinase-mediated Occludin, Claudin-1, and ZO-1
It was concluded that TFs could enhance intestinal barrier function by increasing the expression of TJ-related proteins through the activation of AMPK in Caco-2 cells. Expand
Galactooligosaccharide production by a thermostable β-galactosidase from Sulfolobus solfataricus
The β-galactosidase from S. solfataricus produced GOS with the highest concentration and yield among thermostableβ-galactsosidases reported to date and the final concentration of GOS was maximal at 80°C. Expand
Protease IV, a quorum sensing‐dependent protease of Pseudomonas aeruginosa modulates insect innate immunity
It is suggested that Protease IV provides P. aeruginosa with a sophisticated way to escape the immune attack of host by interfering with the production of AMPs. Expand
Theaflavins, dimeric catechins, inhibit peptide transport across Caco-2 cell monolayers via down-regulation of AMP-activated protein kinase-mediated peptide transporter PEPT1.
It is demonstrated that TFs inhibit peptide transport across Caco-2 cell monolayers, probably through suppression of AMPK-mediated PEPT1 expression, which should be considered a new bioactivity of TFs in black tea. Expand
Growth phase-differential quorum sensing regulation of anthranilate metabolism in Pseudomonas aeruginosa
R and LasR regulate the anthranilate metabolism in a mutually antagonistic and growth phase- differential manner by affecting both the expressions and activities of AntR and PqsR, and that QscR also phase-differentially represses both LasR and RhlR functions in this regulation. Expand
Protective effect of Perilla frutescens cv. Chookyoupjaso mutant water extract against oxidative injury in vitro and in vivo
The aim of this study was to elucidate the protective ability of the Perilla frutescens cv. Chookyoupjaso mutant water extract (PFWE) against oxidative injury in vitro and in vivo. In in vitroExpand
Anthranilate Deteriorates the Structure of Pseudomonas aeruginosa Biofilms and Antagonizes the Biofilm-Enhancing Indole Effect
The results suggest that anthranilate may be a promising antibiofilm agent and antagonize the effect of indole on P. aeruginosa biofilm formation. Expand
Transdermal Eperisone Elicits more Potent and Longer-Lasting Muscle Relaxation than Oral Eperisone
The results suggest that eperisone as transdermal patch form showed efficient absorption with more potent and longer-lasting muscle relaxant activity than oral solution. Expand
Benzotropolone moiety in theaflavins is responsible for inhibiting peptide-transport and activating AMP-activated protein kinase in Caco-2 cells
Objective : In the small intestine, peptide transporter 1 (PEPT1) plays a role in the transport of di- and tri-peptides. Recently, we found that theaflavins (TFs), dimeric catechins, inhibited theExpand