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Data from farmer-owned herds and from experimental matings supported monofactorial recessive inheritance of rectovaginal constriction in US Jersey cattle. Kempthorne's population genetics model of a recessive trait involving only male selection was extended to include mutation and converted to selection of females only. Computer analyses with that model(More)
Nature and cause of bilateral ocular dermoids were investigated by field studies, pedigree analysis, clinical examination, light microscopy, scanning electron microscopy, and transmission electron microscopy. It was determined that ocular dermoids in Hereford cattle are a genetically transmitted defect; characteristics of autosomal recessive and polygenic(More)
The middle and inner ears of 16 dogs, from 1.5 to 17 years of age, with differing degrees of suspected hearing loss were examined. Auditory function was assessed subjectively, and electrophysiologically by recording brainstem auditory-evoked responses (BAER) to click stimuli. Ossicular chains and stapediovestibular articulations were evaluated(More)
Experimental reproduction and ultrastructural findings of spongy degeneration of the central nervous system of hyperammonemic calves are described. Hyperammonemia was produced by intravenous infusion of ammonium acetate. Histologic findings were stereotyped in all calves and characterized by widespread vacuolation of white and grey matter of the brain(More)
When faced with the question of what you should do as a veterinary practitioner, when presented with a congenital defect in a llama, one answer is to seek qualified help from your state veterinary diagnostic laboratory. But most importantly, encourage the owners of such animals to report the defect to their llama association, including pedigree information.(More)
The biotransformation of single oral doses of acetaminophen (APAP) was studied in dogs an cats. Each animal received APAP at a no-effect (low), mildly toxic (medium), and severely toxic (high) dosage; dosages for each species were selected to produce similar clinical effects at each respective dosage. For dogs, these dosages were 100, 200, and 500 mg(More)