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BACKGROUND There is a rising incidence of chronic kidney disease that is likely to pose major problems for both healthcare and the economy in future years. In India, it has been recently estimated that the age-adjusted incidence rate of ESRD to be 229 per million population (pmp), and >100,000 new patients enter renal replacement programs annually. (More)
IgG4 related disease is a fibro-inflammatory condition with involvement of renal and extra renal organs, characterized by lymphoplasmacytic infiltration with organ dysfunction. We describe three cases of IgG4 related renal disease from a tertiary care hospital in south India.
Sunitinib is an oral, multitargeted receptor tyrosine kinase inhibitor of targets such as vascular endothelial growth factor and platelet derived growth factor receptor. It is used for the treatment of metastatic renal cell carcinoma (RCC). Use of sunitinib has been associated with renal dysfunction and nephrotic syndrome. However, simultaneous occurrence(More)
An ultrasound of the neck (SSH-140 A, Toshiba, Japan) was performed followed by CT scan (Somatom CR, Siemens, Erlangen). On sonography we noticed a hypoechoic linear area extending from the neck into the superior mediastinum. It was present between the internal jugular vein and the carotid vessels in the neck and was posteromedial to the sternocleidomastoid(More)
A direct effect of calcitriol on the regulation of the secretion of parathyroid hormone (PTH) has been shown in vitro and in vivo. In patients with renal failure on maintenance hemodialysis, it has been shown that intravenous (IV) administration of calcitriol appears to be superior to continuous oral administration. This may be due to the higher levels of(More)
BACKGROUND For patients who do not have a suitable human leukocyte antigen (HLA)-matched family donor, unrelated donor registries of adult volunteers and banked umbilical cord blood (UCB) units provide the potential for successful haemopoietic stem-cell transplantation. The size and genetic composition of such registries determines the proportion of(More)
Spectrum of causes for renal dysfunction in patients with hematolymphoid malignancy (excluding plasma cell dyscrasia) is varied. A retrospective evaluation of "native" renal biopsies referred to our institute during the period from January 2010 to December 2013 revealed 12 cases. Age ranged between 7 and 69 (median 54.5) years. All patients were males. The(More)
A 50-year-old man presented with pedal edema and episodes of hematuria that had started 1 month before. Systemic examination revealed mild pedal edema and petechial rashes on both lower limbs, without lymphadenopathy. The urine color was noted to be milky white (Figure 1). Urine analysis showed 3þ albumin and numerous red blood cells. Urine spot protein(More)