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Methotrexate, Doxorubicin, and Cisplatin (MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With Resectable High-Grade Osteosarcoma and Good Histologic Response to
Purpose EURAMOS-1, an international randomized controlled trial, investigated maintenance therapy with pegylated interferon alfa-2b (IFN-α-2b) in patients whose osteosarcoma showed good histologicExpand
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Inhibin B is superior to FSH as a serum marker for spermatogenesis in men treated for Hodgkin's lymphoma with chemotherapy during childhood.
BACKGROUND The aim of this study was to evaluate the long-term gonadal sequelae after treatment for childhood Hodgkin's lymphoma with combination chemotherapy, using up to date fertility parametersExpand
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Anti-Mullerian hormone is a sensitive serum marker for gonadal function in women treated for Hodgkin's lymphoma during childhood.
PURPOSE The aim of this study was to evaluate the long-term effects of combination chemotherapy treatment for girls with Hodgkin's lymphoma (HL) on gonadal function using anti-Müllerian hormone (AMH)Expand
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The value of local treatment in patients with primary, disseminated, multifocal Ewing sarcoma (PDMES)
The value of local treatment in patients with primary, disseminated, multifocal Ewing sarcoma (PDMES) was investigated.
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Photodynamic therapy with verteporfin for choroidal neovascularization caused by age-related macular degeneration: results of retreatments in a phase 1 and 2 study.
OBJECTIVES To evaluate safety and short-term visual acuity and fluorescein angiographic effects of photodynamic therapy (PDT) after retreatments with verteporfin for choroidal neovascularizationExpand
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Predictors of uptake of human immunodeficiency virus testing by tuberculosis patients in Free State Province, South Africa.
SETTING Two districts of the Free State Province in South Africa. OBJECTIVE To determine the predictors of human immunodeficiency virus (HIV) test uptake by tuberculosis (TB) patients. DESIGN AExpand
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The Baxα:Bcl‐2 ratio modulates the response to dexamethasone in leukaemic cells and is highly variable in childhood acute leukaemia
Bcl‐2 over‐expression has been shown to inhibit apoptosis induced by a variety of stimuli, whereas a predominance of Baxα to Bcl‐2 accelerates apoptosis upon apoptotic stimuli. We sought to study theExpand
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Medical interventions for the prevention of platinum-induced hearing loss in children with cancer.
BACKGROUND Platinum-based therapy, including cisplatin, carboplatin, oxaliplatin or a combination of these, is used to treat a variety of paediatric malignancies. One of the most important adverseExpand
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Pathophysiological Mechanisms of Severe Anaemia in Malawian Children
Background Severe anaemia is a major cause of morbidity and mortality in African children. The aetiology is multi-factorial, but interventions have often targeted only one or a few causal factors,Expand
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Malaria control in rural Malawi: implementing peer health education for behaviour change
BackgroundInterventions to reduce malaria burden are effective if communities use them appropriately and consistently. Several tools have been suggested to promote uptake and use of malaria controlExpand
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