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Interaction with CBP/p300 enables the bovine papillomavirus type 1 E6 oncoprotein to downregulate CBP/p300-mediated transactivation by p53.
The E6 oncoprotein of bovine papillomavirus type 1 (BPV-1) can transform cells independently of p53 degradation. The precise mechanisms underlying this transformation are not yet completelyExpand
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Expression of Drop1, a gene encoding a 350 kDa protein, is downregulated in epithelial malignancies
2713 In a study employing differential display analysis to identify differentially expressed genes in ovarian carcinomas, we found an 11 kb mRNA coding for a 350 kDa Protein suppressed in over 70% ofExpand