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Expression features of SOX9 associate with tumor progression and poor prognosis of hepatocellular carcinoma
BackgroundSOX9 as a member of the SOX (SRY [sex determining region Y] box) gene superfamily has been previously demonstrated to be a proto-oncogene in a variety of malignancies. However, the clinicalExpand
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Deep sequencing–based comparative transcriptional profiles of Cymbidium hybridum roots in response to mycorrhizal and non-mycorrhizal beneficial fungi
BackgroundThe Orchidaceae is one of the largest families in the plant kingdom and orchid mycorrhizae (OM) are indispensable in the life cycle of all orchids under natural conditions. In spite ofExpand
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Baicalin reduces the permeability of the blood-brain barrier during hypoxia in vitro by increasing the expression of tight junction proteins in brain microvascular endothelial cells.
ETHNOPHARMACOLOGICAL RELEVANCE Baicalin is one of the principal flavonoids isolated from the dried root of Scutellariae Baicalensis Georgi and has been widely used as a traditional herbal medicine toExpand
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Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Delivers Heat Shock Protein 60-Fused Antigen into the MHC Class I Presentation Pathway
Heat shock protein (Hsp) 60 elicits a potent proinflammatory response in the innate immune system and has been proposed as a danger signal of stressed or damaged cells to the immune system. PreviousExpand
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Laminarin-mediated targeting to Dectin-1 enhances antigen-specific immune responses.
It has immense potential for immunotherapy and vaccination to target antigens to antigen-presenting cells (APCs). Here we described a method for delivering whole protein antigens to APCs viaExpand
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The effects of allitridi and amiodarone on the conduction system and reverse use-dependence in the isolated hearts of rats with myocardial infarction.
ETHNOPHARMACOLOGICAL RELEVANCE Allium sativum L. (DaSuan in Mandarin) is a traditional Chinese herb that has been used to prevent and heal cardiovascular diseases. OBJECTIVE To study the effects ofExpand
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New metabolites from the biotransformation of ginsenoside Rb1 by Paecilomyces bainier sp.229 and activities in inducing osteogenic differentiation by Wnt/β-catenin signaling activation
Background Ginseng is a well-known traditional Chinese medicine that has been widely used in a range of therapeutic and healthcare applications in East Asian countries. Microbial transformation isExpand
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Characterization and immunostimulatory activity of a polysaccharide from the spores of Ganoderma lucidum.
Spores of Ganoderma lucidum contain a large amount of bioactive substances and have a higher bioactivity than the fruit bodies of G. lucidum. However, ingredients from spores are less studied due toExpand
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Baicalin benefits the anti‐HBV therapy via inhibiting HBV viral RNAs
Background: Although current antiviral treatments (nucleoside analogs, NAs) for chronic hepatitis B virus (HBV) infection are effective in suppressing HBV‐DNA replication, their clinical outcomes canExpand
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Effect of Wenxin Granules on Gap Junction and MiR-1 in Rats with Myocardial Infarction
Myocardial infarction (MI) patients are at high risk of potential lethal arrhythmia. Gap junction and microRNA-1 (miR-1) are both arrhythmia generating conditions. The present study investigatedExpand
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