• Publications
  • Influence
Rtt106p is a histone chaperone involved in heterochromatin-mediated silencing.
Epigenetic inheritance of heterochromatin structure is an important cellular process whose mechanism remains elusive. In this article, we describe the identification of nine enhancers of theExpand
  • 115
  • 19
  • PDF
A new method for purification of recombinant human alpha-synuclein in Escherichia coli.
alpha-Synuclein (AS), a major component of Lewy body in Parkinson's disease patients, exists as a natively unfolded protein in physiological buffer. We recently found that the overexpressed AS inExpand
  • 128
  • 9
  • PDF
Improving 2-Phenylethanol Production via Ehrlich Pathway Using Genetic Engineered Saccharomyces cerevisiae Strains
Abstract2-phenylethanol (2-PE) is an important aromatic compound with a rose-like fragrance widely used in food industry and cosmetic manufacture. In order to obtain “natural” 2-PE, the geneticallyExpand
  • 34
  • 6
ROLE OF CYP2C9 AND ITS VARIANTS (CYP2C9*3 AND CYP2C9*13) IN THE METABOLISM OF LORNOXICAM IN HUMANS
  • Yingjie Guo, Yifan Zhang, +5 authors H. Zhou
  • Biology, Medicine
  • Drug Metabolism and Disposition
  • 1 June 2005
CYP2C9 is an important member of the cytochrome P450 enzyme superfamily with some 12 CYP2C9 alleles (*1-*12) being previously reported. Recently, we identified a new CYP2C9 allele with a Leu90ProExpand
  • 68
  • 4
Discovery of Protein–lncRNA Interactions by Integrating Large-Scale CLIP-Seq and RNA-Seq Datasets
Long non-coding RNAs (lncRNAs) are emerging as important regulatory molecules in developmental, physiological, and pathological processes. However, the precise mechanism and functions of most ofExpand
  • 54
  • 3
  • PDF
Genetic variability in Gymnodiniaceae ITS regions: implications for species identification and phylogenetic analysis
The internal transcribed spacer (ITS) regions and 5.8S rRNA genes from several strains of toxic Gymnodiniaceae were sequenced and subjected to phylogenetic analysis with other Gymnodiniaceae species.Expand
  • 35
  • 3
Mitochondrial DNA analysis provides new insights into the origin of the Chinese domestic goat
Abstract Many studies have focused on modern goats, however, few reports focused on origin and genetic structure of Chinese ancient goats. In this study, we analyzed the 289-bp fragment ofExpand
  • 17
  • 3
Mitochondrial DNA analysis of human remains from the Yuansha site in Xinjiang, China
The Yuansha site is located in the center of the Taklimakan Desert of Xinjiang, in the southern Silk Road region. MtDNA was extracted from fifteen human remains excavated from the Yuansha site,Expand
  • 15
  • 2
Subtype and sequence analysis of HIV-1 strains in Heilongjiang Province.
BACKGROUND Human immunodeficiency virus (HIV-1) is divided into two types, HIV-1 (groups M, N and O) and HIV-2. Heilongjiang Province located in the northeast of China, and the feature of the subtypeExpand
  • 10
  • 1
Pan-cancer analysis of clinical relevance of alternative splicing events in 31 human cancers
Alternative splicing represents a critical posttranscriptional regulation of gene expression, which contributes to the protein complexity and mRNA processing. Defects of alternative splicingExpand
  • 16
  • 1