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Genetics and Pathogenesis of Diffuse Large B‐Cell Lymphoma
Background Diffuse large B‐cell lymphomas (DLBCLs) are phenotypically and genetically heterogeneous. Gene‐expression profiling has identified subgroups of DLBCL (activated B‐cell–like [ABC],Expand
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Data Security and Privacy Protection Issues in Cloud Computing
  • Deyan Chen, H. Zhao
  • Computer Science
  • International Conference on Computer Science and…
  • 23 March 2012
This paper provides a concise but all-round analysis on data security and privacy protection issues associated with cloud computing across all stages of data life cycle. Expand
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A spectral boundary integral method for flowing blood cells
A spectral boundary integral method for simulating large numbers of blood cells flowing in complex geometries is developed and demonstrated. Expand
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A fixed-mesh method for incompressible flow-structure systems with finite solid deformations
A fixed-mesh algorithm is proposed for simulating flow-structure interactions such as those occurring in biological systems, in which both the fluid and solid are incompressible and the solid deformations are large. Expand
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New Era in Drug Interaction Evaluation: US Food and Drug Administration Update on CYP Enzymes, Transporters, and the Guidance Process
Predicting clinically significant drug interactions during drug development is a challenge for the pharmaceutical industry and regulatory agencies. Since the publication of the US Food and DrugExpand
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Texture Feature Analysis for Computer-Aided Diagnosis on Pulmonary Nodules
We compared three well-known types of two-dimensional (2D) texture features (Haralick, Gabor, and local binary patterns or local binary pattern features) on CADx of lung nodules using the largest public database founded by Lung Image Database Consortium and Image Database Resource Initiative and then investigated extension from 2D to three-dimensional space. Expand
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Variable Fitness Impact of HIV-1 Escape Mutations to Cytotoxic T Lymphocyte (CTL) Response
Human lymphocyte antigen (HLA)-restricted CD8+ cytotoxic T lymphocytes (CTL) target and kill HIV-infected cells expressing cognate viral epitopes. This response selects for escape mutations withinExpand
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Translation and validation of the Standard Chinese version of the EORTC QLQ-C30
The majority of quality of life (QOL) questionnaires have been developed and used in English-speaking or Western European countries. The aims of this study were to provide the Standard ChineseExpand
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Crystal structure, conformational fixation, and entry-related interactions of mature ligand-free HIV-1 Env
As the sole viral antigen on the HIV-1–virion surface, trimeric Env is a focus of vaccine efforts. Here we present the structure of the ligand-free HIV-1–Env trimer, fix its conformation andExpand
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Essential role of the linear ubiquitin chain assembly complex in lymphoma revealed by rare germline polymorphisms.
UNLABELLED Constitutive activation of NF-κB is a hallmark of the activated B cell-like (ABC) subtype of diffuse large B-cell lymphoma (DLBCL), owing to upstream signals from the B-cell receptor (BCR)Expand
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