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A reference panel of 64,976 haplotypes for genotype imputation
We describe a reference panel of 64,976 human haplotypes at 39,235,157 SNPs constructed using whole-genome sequence data from 20 studies of predominantly European ancestry. Using this resource leadsExpand
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Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1) provides insights into genome evolution
Gossypium hirsutum has proven difficult to sequence owing to its complex allotetraploid (AtDt) genome. Here we produce a draft genome using 181-fold paired-end sequences assisted by fivefoldExpand
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Identifying relevant studies in software engineering
Context: Systematic literature review (SLR) has become an important research methodology in software engineering since the introduction of evidence-based software engineering (EBSE) in 2004. OneExpand
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Loss-of-function mutations in APOC3, triglycerides, and coronary disease.
BACKGROUND Plasma triglyceride levels are heritable and are correlated with the risk of coronary heart disease. Sequencing of the protein-coding regions of the human genome (the exome) has theExpand
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Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk
Blood lipid levels are heritable, treatable risk factors for cardiovascular disease. We systematically assessed genome-wide coding variation to identify new genes influencing lipid traits, fine mapExpand
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Structural genomic changes underlie alternative reproductive strategies in the ruff (Philomachus pugnax)
The ruff is a Palearctic wader with a spectacular lekking behavior where highly ornamented males compete for females. This bird has one of the most remarkable mating systems in the animal kingdom,Expand
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Towards an Evidence-Based Understanding of Electronic Data Sources
Systematic Literature Reviews and Systematic Mapping Studies are relatively new forms of secondary studies in software engineering. Identifying relevant papers from various Electronic Data SourcesExpand
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Systematic reviews in software engineering: An empirical investigation
Background Systematic Literature Reviews (SLRs) have gained significant popularity among Software Engineering (SE) researchers since 2004. Several researchers have also been working on improving theExpand
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Abundant expression of Dec1/stra13/sharp2 in colon carcinoma: its antagonizing role in serum deprivation-induced apoptosis and selective inhibition of procaspase activation.
The basic helix-loop-helix (bHLH) proteins are intimately associated with developmental events such as cell differentiation and lineage commitment. The HLH domain in the bHLH motif is responsible forExpand
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Exome-wide association study of plasma lipids in >300,000 individuals
We screened variants on an exome-focused genotyping array in >300,000 participants (replication in >280,000 participants) and identified 444 independent variants in 250 loci significantly associatedExpand
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