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- Publications
- Influence
Toxicity of 100 nm zinc oxide nanoparticles: a report of 90-day repeated oral administration in Sprague Dawley rats
- Yu-Ri Kim, J. Park, +18 authors Meyoung-kon Kim
- Materials Science, Medicine
- International journal of nanomedicine
- 15 December 2014
Nanoparticles (NPs) are used commercially in health and fitness fields, but information about the toxicity and mechanisms underlying the toxic effects of NPs is still very limited. The aim of this… Expand
Pharmacokinetics of florfenicol and its metabolite, florfenicol amine, in dogs.
- B. Park, Jong-Hwan Lim, M. Kim, Y. Hwang, H. Yun
- Chemistry, Medicine
- Research in veterinary science
- 1 February 2008
A study on the bioavailability and pharmacokinetics of florfenicol was conducted in six healthy dogs following a single intravenous (i.v.) or oral (p.o.) dose of 20 mg kg(-1) body weight (b.w.).… Expand
Embryo lethality and teratogenicity of a new fluoroquinolone antibacterial DW-116 in rats
- J. Kim, H. Yun, Ho-chul Shin, Sang-Seop Han, Moon-Koo Chung
- Biology, Medicine
- Archives of Toxicology
- 1 April 2000
Abstract DW-116, 1-(5-fluoro-2-pyridyl)-6-fluoro-7-(4-methyl-l-piperazinyl)-1, 4-dihydro-4-oxoquinolone-3-carboxylic acid hydrochloride, is a newly developed fluoroquinolone antibacterial. The… Expand
Lipopolysaccharide-binding and neutralizing activities of surfactin C in experimental models of septic shock.
- Y. Hwang, B. Park, +4 authors H. Yun
- Biology, Medicine
- European journal of pharmacology
- 5 February 2007
To evaluate the anti-endotoxin activity of surfactin C, we studied its lipopolysaccharide-binding activity in vitro and therapeutic efficacy in experimental models of gram-negative septic shock. The… Expand
Surfactin C inhibits the Lipopolysaccharide-induced Transcription of Interleukin-1β and Inducible Nitric Oxide Synthase and
Nitric Oxide Production in Murine RAW 264.7 Cells
- Mi-Hyun Hwang, Jong-Hwan Lim, +4 authors S. Park
- Chemistry, Medicine
- Biotechnology Letters
- 1 October 2005
The anti-inflammatory activity of the surfactin C derived from Bacillus subtilis isolate was investigated in lipopolysaccharide (LPS, 1 μg ml−1)-treated mouse RAW 264.7 cells. LPS increased mRNA… Expand
Plasma disposition of toltrazuril and its metabolites, toltrazuril sulfoxide and toltrazuril sulfone, in rabbits after oral administration.
- M. Kim, Jong-Hwan Lim, Y. Hwang, B. Park, In-Bae Song, H. Yun
- Biology, Medicine
- Veterinary parasitology
- 19 April 2010
The objective of this study was to evaluate the pharmacokinetic profiles of toltrazuril (TZR), and its major metabolites toltrazuril sulfoxide (TZR x SO) and toltrazuril sulfone (TZR x SO(2)) in… Expand
Subacute (28 day) Toxicity of Surfactin C, a Lipopeptide Produced by Bacillus subtilis, in Rats
Surfactin C, produced by acillus subtilis isolated from Korean soybean paste, was given to Sprague-Dawley rats of both sexes at dose of 500, 1000 or 2000 mg/kg for 28 days. There were no surfactin… Expand
Comparative pharmacokinetics of tylosin or florfenicol after a single intramuscular administration at two different doses of tylosin-florfenicol combination in pigs.
- Mi-Hee Kim, E. Gebru, +6 authors S. Park
- Chemistry, Medicine
- The Journal of veterinary medical science
- 25 January 2008
Clinical pharmacokinetic profiles were investigated following intramuscular (i.m.) administration to pigs with a commercial tylosin-florfenicol combination product at a dose of 2.5 mg/kg tylosin and… Expand
Assessment of dermal safety of Scutellaria baicalensis aqueous extract topical application on skin hypersensitivity.
- T. Kim, In-Bae Song, +5 authors H. Yun
- Medicine
- Planta medica
- 1 July 2013
Scutellaria baicalensis has been used as a traditional herbal medicine for bronchitis, hepatitis, and allergic diseases. The root of Scutellaria baicalensis contains active flavonoid components,… Expand
Surfactin C inhibits Mycoplasma hyopneumoniae-induced transcription of proinflammatory cytokines and nitric oxide production in murine RAW 264.7 cells
- Mi-Hyun Hwang, Zhi-qiang Chang, +5 authors S. Park
- Biology, Medicine
- Biotechnology Letters
- 1 February 2008
Intact pathogenic Mycoplasma hyopneumoniae at 100 μg protein ml−1 induced transcription of proinflammatory cytokines such as cyclooxygenase (COX)-2, tumor necrosis factor (TNF)-α, interleukin(IL)-1,… Expand