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Development and characterization of an orodispersible film containing drug nanoparticles.
In this study, a novel orodispersible film (ODF) containing drug nanoparticles was developed with the goal of transforming drug nanosuspensions into a solid dosage form and enhancing oralExpand
Hepatitis B virus inhibiting constituents from Herpetospermum caudigerum.
From the ethanol extract of the seeds of Herpetospermum caudigerum wall, one new lignan compound 1, was isolated and characterized along with three known compounds 2, 3 and 4. The structureExpand
Controlled release of cyclosporine A self-nanoemulsifying systems from osmotic pump tablets: near zero-order release and pharmacokinetics in dogs.
  • Xi Zhang, Y. Yi, +5 authors W. Wu
  • Chemistry, Medicine
  • International journal of pharmaceutics
  • 16 August 2013
It is very important to enhance the absorption simultaneously while designing controlled release delivery systems for poorly water-soluble and poorly permeable drugs (BCS IV). In this study,Expand
Process optimization, characterization and evaluation in vivo of oxymatrine-phospholipid complex.
The objective of this study was to prepare oxymatrine-phospholipid complex (OMT-PLC) to enhance oral bioavailability of oxymatrine. A central composite design approach was used for processExpand
Hepatoprotective effects of lignans extract from Herpetospermum caudigerum against CCl₄-induced acute liver injury in mice.
ETHNOPHARMACOLOGICAL RELEVANCE Herpetospermum caudigerum (HCD) is traditionally used for the treatment of liver diseases, cholic diseases, and dyspepsia as a well-known Tibetan medicine in China. TheExpand
Development of poly(N-isopropylacrylamide)/alginate copolymer hydrogel-grafted fabrics embedding of berberine nanosuspension for the infected wound treatment
In the present study, a novel hydrogel-grafted fabrics embedding of berberine nanosuspension was developed for the treatment of infected wound. Hydrogel-grafted fabric was prepared by graftExpand
Binary lipids-based nanostructured lipid carriers for improved oral bioavailability of silymarin
The main purpose of this study was to prepare binary lipids-based nanostructured lipid carriers to improve the oral bioavailability of silymarin, a poorly water-soluble liver protectant.Expand
Process optimization and evaluation of novel baicalin solid nanocrystals
The objective of this study was to prepare baicalin solid nanocrystals (BCN-SNS) to enhance oral bioavailability of baicalin. A Box–Behnken design approach was used for process optimization. TheExpand
A hepatitis B virus inhibitory neolignan from Herpetospermum caudigerum.
A new dihydrobenzofuran neolignan, herpepropenal, was isolated from the seeds of Herpetospermum caudigerum. Its chemical structure was established based on spectroscopic analysis. In this work, theExpand
Preparation, characterization, and pharmacokinetic evaluation of puerarin submicron emulsion.
A novel formulation of puerarin was studied. Puerarin submicron emulsion was prepared by complex phase inversion-high-pressure homogenization technology. Characterization, distribution of drug inExpand