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Genome-Wide Mapping of the Cohesin Complex in the Yeast Saccharomyces cerevisiae
In eukaryotic cells, cohesin holds sister chromatids together until they separate into daughter cells during mitosis. We have used chromatin immunoprecipitation coupled with microarray analysis (ChIPExpand
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A Maize Homolog of Mammalian CENPC Is a Constitutive Component of the Inner Kinetochore
Genes for three maize homologs (CenpcA, CenpcB, and CenpcC) of the conserved kinetochore assembly protein known as centromere protein C (CENPC) have been identified. The C-terminal portion of maizeExpand
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The Maize Homologue of the Cell Cycle Checkpoint Protein MAD2 Reveals Kinetochore Substructure and Contrasting Mitotic and Meiotic Localization Patterns
We have identified a maize homologue of yeast MAD2, an essential component in the spindle checkpoint pathway that ensures metaphase is complete before anaphase begins. Combined immunolocalization ofExpand
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Pds5 is required for homologue pairing and inhibits synapsis of sister chromatids during yeast meiosis
A meiosis-conditional pds5 allele in yeast provides a more detailed understanding of homologue pairing and synaptonemal complex formation.
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Meiotic condensin is required for proper chromosome compaction, SC assembly, and resolution of recombination-dependent chromosome linkages
Condensin is an evolutionarily conserved protein complex that helps mediate chromosome condensation and segregation in mitotic cells. Here, we show that condensin has two activities that contributeExpand
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The Aurora kinase Ipl1 maintains the centromeric localization of PP2A to protect cohesin during meiosis
Homologue segregation during the first meiotic division requires the proper spatial regulation of sister chromatid cohesion and its dissolution along chromosome arms, but its protection atExpand
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Neocentromere-mediated Chromosome Movement in Maize
Neocentromere activity is a classic example of nonkinetochore chromosome movement. In maize, neocentromeres are induced by a gene or genes on Abnormal chromosome 10 (Ab10) which causesExpand
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Chromosome Morphogenesis: Condensin-Dependent Cohesin Removal during Meiosis
During meiosis, segregation of homologous chromosomes necessitates the coordination of sister chromatid cohesion, chromosome condensation, and recombination. Cohesion and condensation require the SMCExpand
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Functional Redundancy in the Maize Meiotic Kinetochore
  • H. Yu, R. Dawe
  • Biology, Medicine
  • The Journal of cell biology
  • 2 October 2000
Kinetochores can be thought of as having three major functions in chromosome segregation: (a) moving plateward at prometaphase; (b) participating in spindle checkpoint control; and (c) movingExpand
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The plant kinetochore.
Kinetochores are large protein complexes that bind to centromeres. By interacting with microtubules and their associated motor proteins, kinetochores both generate and regulate chromosome movement.Expand
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