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Adaptive diversification of bitter taste receptor genes in Mammalian evolution.
The diversity and evolution of bitter taste perception in mammals is not well understood. Recent discoveries of bitter taste receptor (T2R) genes provide an opportunity for a genetic approach to this… Expand
Genome-wide cloning and sequence analysis of leucine-rich repeat receptor-like protein kinase genes in Arabidopsis thaliana
BackgroundTransmembrane receptor kinases play critical roles in both animal and plant signaling pathways regulating growth, development, differentiation, cell death, and pathogenic defense responses.… Expand
Functional genomics of genes with small open reading frames (sORFs) in S. cerevisiae.
Genes with small open reading frames (sORFs; <100 amino acids) represent an untapped source of important biology. sORFs largely escaped analysis because they were difficult to predict computationally… Expand
The formation of tetraploid stocks of red crucian carp×common carp hybrids as an effect of interspecific hybridization
Abstract F 3 –F 8 hybrids of red crucian carp ( Carassius auratus red var.) (♀)×common carp ( Cyprinus carpio L.) (♂) were found to be allotetraploids by examining the numbers and karyotypes of… Expand
Adaptive Diversification of Vomeronasal Receptor 1 Genes in Rodents
The vomeronasal receptor 1 (V1R) are believed to be pheromone receptors in rodents. Here we used computational methods to identify 95 and 62 new putative V1R genes from the draft rat and mouse genome… Expand
Budding yeast PDS5 plays an important role in meiosis and is required for sister chromatid cohesion
Budding yeast PDS5 is an essential gene in mitosis and is required for chromosome condensation and sister chromatid cohesion. Here we report that PDS also is required in meiosis. Pds5p localizes on… Expand
The Role of Bile Salt Export Pump Gene Repression in Drug-Induced Cholestatic Liver Toxicity
- Brandy Garzel, H. Yang, L. Zhang, S. Huang, J. Polli, Hongbing Wang
- Biology, Medicine
- Drug Metabolism and Disposition
- 1 March 2014
The bile salt export pump (BSEP, ABCB11) is predominantly responsible for the efflux of bile salts, and disruption of BSEP function is often associated with altered hepatic homeostasis of bile acids… Expand
The expression of AmphiTCTP, a TCTP orthologous gene in amphioxus related to the development of notochord and somites.
- Zhongke Chen, H. Zhang, H. Yang, Xiangwei Huang, X. Zhang, P. Zhang
- Biology, Medicine
- Comparative biochemistry and physiology. Part B…
- 1 July 2007
The translationally controlled tumor protein (TCTP) is highly conserved and has been widely found in eukaryotic organisms. Here, we report the phylogenetic analysis and developmental expression of… Expand
Whole-Genome Sequencing Identifies a Novel Variation of WAS Gene Coordinating With Heterozygous Germline Mutation of APC to Enhance Hepatoblastoma Oncogenesis
Hepatoblastoma (HB), a leading primary hepatic malignancy in children, originates from primitive hepatic stem cells. This study aimed to uncover the genetic variants that are responsible for HB… Expand
Ribbing disease (multiple diaphyseal sclerosis): a case report and literature review
- L. L. Zhang, W. Jiang, X. Li, J. Yuan, H. Yang
- Journal of orthopaedic science : official journal…
- 1 November 2011
Abstract Ribbing disease is a rare condition of diaphyseal sclerosis first described by Ribbing , characterized by benign endosteal and periosteal bone growth confined to the diaphyses of the long… Expand