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In vitro and in vivo antimalarial activities of a non-glycosidic 18-membered macrolide antibiotic, borrelidin, against drug-resistant strains of Plasmodia.
TLDR
The antimalarial profile of borrelidin is reported here, a known nonglycosidic 18-membered macrolide antibiotic with a cyclopentanecarboxylic acid side chain, in comparison with those of clinically used antimalaria drugs. Expand
Medicinal use of Cochlospermum tinctorium in Mali Anti-ulcer-, radical scavenging- and immunomodulating activities of polymers in the aqueous extract of the roots.
TLDR
It is shown that the polysaccharides are partly responsible for the bioactivities observed in vitro and may be responsible forThe anti-ulcer activities observed. Expand
Complement-activating polysaccharides from medicinal herbs
The complement system consists of over 20 serum proteins including nine com-plement components (C1 to C9) and their regulators, and is normally present in blood serum in an inactive form. The systemExpand
In vitro antimalarial activity of biflavonoids from Wikstroemia indica.
TLDR
In this investigation of in vitro antimalarial screening of medicinal herbal extracts, the n-BuOH extract from the root of Wikstroemia indica showed a potent inhibitory effect and two biflavonoids were isolated, 1 and 2 of which were confirmed by (1)H- and (13)C-NMR. Expand
Antitrypanosomal activity of some pregnane glycosides isolated from Caralluma species.
TLDR
Pregnane glycosides previously isolated from genus Caralluma (C. Penicillata, C. tuberculata and C. russelliana) were tested and it was noticed that acylation is required for the antitrypanosomal activity while glycosylation at C-20 has no significant effect on the activity. Expand
Pectic polysaccharides from Chinese herbs: structure and biological activity
Bioactive pectic polysaccharides have been isolated from Chinese herbs, and their structure, activity and modes of action have been studied. Complement-activating pectin from Angelica acutilobaExpand
Anti-influenza virus activity of biflavonoids.
Ginkgetin was found to inhibit the influenza virus sialidase. Ginkgetin-sialic acid conjugates showed a significant survival effect in the influenza-virus-infected mice.
New lycorine-type alkaloid from Lycoris traubii and evaluation of antitrypanosomal and antimalarial activities of lycorine derivatives.
TLDR
A new lycorine derivative LT1 was isolated from the aerial part and bulbs of Lycoris traubii Hayward and established by spectroscopic analysis and semi-synthesis to be 1-O-(3'S)-hydroxybutanoyllycorine, which showed significant activity against P. falciparum in an in vitro experiment. Expand
In vitro antimalarial activity of prenylated flavonoids from Erythrina fusca
TLDR
Ethyl acetate extract from the stem bark of Erythrina fusca showed a antimalarial activity against the multi-drug-resistant strain (K1) of Plasmodium falciparum, and six flavonoids, lupinifolin, citflavanone, erythrisenegalone, lonchocarpol A, and 8-prenyldaidzein were isolated from the extract. Expand
Combination Effects of Herbs in a Multi-herbal Formula: Expression of Juzen-taiho-to's Immuno-modulatory Activity on the Intestinal Immune System
TLDR
3D-HPLC analysis of the ingredients in the fractions from the combined decoctions indicated that, in addition to quantitative changes of ingredients, alterations occur in their chemical composition by decoction of different herbs. Expand
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