H. Yajima

Publications17
h-index8
Citations580
Highly Influential Citations29
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Isohumulones, Bitter Acids Derived from Hops, Activate Both Peroxisome Proliferator-activated Receptor α and γ and Reduce Insulin Resistance*
The peroxisome proliferator-activated receptors (PPARs) are dietary lipid sensors that regulate fatty acid and carbohydrate metabolism. The hypolipidemic effects of fibrate drugs and the therapeutic… Expand
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Prevention of diet-induced obesity by dietary black tea polyphenols extract in vitro and in vivo.
OBJECTIVE The effects of certain tea components on the prevention of obesity in humans have recently been reported, although it is still unclear whether black tea consumption is beneficial. We… Expand
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Isohumulones, bitter acids derived from hops, activate both peroxisome proliferator-activated receptor alpha and gamma and reduce insulin resistance.
The peroxisome proliferator-activated receptors (PPARs) are dietary lipid sensors that regulate fatty acid and carbohydrate metabolism. The hypolipidemic effects of fibrate drugs and the therapeutic… Expand
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Constituents from the leaves of Nelumbo nucifera stimulate lipolysis in the white adipose tissue of mice.
Nelumbo nucifera Gaertn. (Nymphaceae) has been used for various medicinal purposes as in Chinese herbal medicine. In particular, the leaves are known for diuretic and astringent properties, and are… Expand
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Prevention of diet-induced obesity by dietary isomerized hop extract containing isohumulones, in rodents
OBJECTIVE:Isomerized hop extract (IHE), which consists mainly of isohumulones and is required in the beer brewing process, was investigated for its effects on diet-induced obesity in two strains of… Expand
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Isohumulones, the bitter component of beer, improve hyperglycemia and decrease body fat in Japanese subjects with prediabetes.
BACKGROUND & AIMS A recent study reported that isohumulones, the bitter component of beer, activate peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARgamma in vitro and decrease… Expand
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Identification of peroxisome-proliferator responsive element in the mouse HSL gene.
Hormone-sensitive lipase (HSL) catalyzes the rate-limiting step of lipolysis in adipose tissue. Several studies suggest that protein phosphorylation regulates the HSL enzymatic activity. On the other… Expand
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Quercetin-3-O-glucuronide induces ABCA1 expression by LXRα activation in murine macrophages.
Reverse cholesterol transport (RCT) removes excess cholesterol from macrophages to prevent atherosclerosis. ATP-binding cassette, subfamily A, member 1 (ABCA1) is a crucial cholesterol transporter… Expand
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Anti-obesity Effects of a Dietary Isomerized Hop Extract Containing Isohumulones Generated via Peroxisome Proliferators-Activated Receptors
Abstract Isomerized hop extract (IHE), which consists mainly of isohumulones and is required in the beer-brewing process, was investigated for its effects on diet-induced obesity. Supplementation of… Expand
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Roasted Barley Extract Affects Blood Flow in the Rat Tail and Increases Cutaneous Blood Flow and Skin Temperature in Humans.
Roasted barley extract (RBE, "Mugicha") is a traditional Japanese beverage reported to improve blood viscosity and affect food functionality. RBE is suggested to contain 2,5-diketopiperazines, which… Expand
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