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Interaction of antidepressant and antipsychotic drugs with the human organic cation transporters hOCT1, hOCT2 and hOCT3
TLDR
Under the assumption of a tenfold accumulation in the brain, bupropion, nefazodone and clozapine may notably inhibit the corresponding hOCTs and it remains to be shown whether such a direct inhibition plays a role in the clinical effects of these three drugs. Expand
Detection of Phenobarbital and Seven Other Sedative Hypnotics Illegally Adulterated into Traditional Chinese Medicines and Health Foods by HPLC-DAD
TLDR
This HPLC-DAD method is fast,sensitive and propagable for the detection of 8 sedative hypnotics illegally adulterated into traditional Chinese medicines and health foods. Expand
Effect of oviductus ranae on hepatic fibrosis in rat
TLDR
Oviductus ranae can protect hepatocytes from injury, reduce hepatic fibrosis in rat liver tissue collagen proliferation,increase antioxidant capacity, delay the formation of cirrhosis of hepatics fibrosis, have a good therapeutic effect and prevent the progression of hepatic Fibrosis in rats. Expand
Factors Affecting the Extraction of Heavy Metals in Sediments Using Biodegradable [S,S]-ethylene diamine disuccinic acid
A biodegradable chelating agent,[S,S] -stereoisomer of ethylenediamine disuccinate([S,S] -EDDS),has been investigated as a potential washing/leaching agent to replace ethylenediaminetetraacetic acidExpand
Speciation of Heavy Metals and Pb Stable Isotope Signatures in Urban Channel Sediments in Nanjing
In order to investigate the mobile potentiality and the characteristics of heavy metal contamination sources in urban channel sediments,samples were collected from urban channels in residential areasExpand
Formation of N-(Nitrosomethyl)urea in stomachs of experimental pigs and human volunteers given fish sauce in vivo.
  • D. Deng, H. Xin
  • Chemistry, Medicine
  • Journal of agricultural and food chemistry
  • 23 May 2000
TLDR
There is intragastric formation of NMU, even at natural amounts of nitrite, in the gastric lumen of both models in vivo and that the formation was nitrite- and pH-dependent. Expand
Dipeptidyl peptidase IV inhibitors for the treatment of type 2 diabetes
The present paper summarized the dipeptidyl peptidase Ⅳ(DPP-Ⅳ) and the clinical studies of DPP-Ⅳ inhibitors.DPP-Ⅳ reduces the degradation of GLP-1 and GIP,which stimulate insulin secretion.InhibitionExpand
[A study on formation of N-(nitrosomethyl) urea in experimental pig stomach gavaged with fish sauce].
TLDR
It is postulated that N-nitrosamides, such as NMU could be formed endogenously in the stomachs of local residents who consume fish sauce often and have a higher exposure to nitrite in their stomachs. Expand
Extractability of Cu,Zn,Pb and Cd in Municipal Sludges Using a Biodegradable Chelating Agent- Stereoisomer of Ethylenediamine Disuccinate
A biodegradable chelating agent- stereoisomer of ethylenediamine disuccinate(EDDS) was used to extract Cu,Zn,Cd,and Pb in municipal sludges from different sources.The research on extraction kineticExpand
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