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Adaptive Servo-Ventilation for Central Sleep Apnea in Systolic Heart Failure.
BACKGROUND Central sleep apnea is associated with poor prognosis and death in patients with heart failure. Adaptive servo-ventilation is a therapy that uses a noninvasive ventilator to treat centralExpand
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Fluorine-18-FDG and iodine-131-iodide uptake in thyroid cancer.
UNLABELLED We conducted a prospective study to define the sensitivity of 131I scintigraphy and 18FDG PET whole-body scanning in the detection of thyroid cancer and metastases. METHODS Forty-oneExpand
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Rationale and design of the SERVE-HF study: treatment of sleep-disordered breathing with predominant central sleep apnoea with adaptive servo-ventilation in patients with chronic heart failure
Central sleep apnoea/Cheyne–Stokes respiration (CSA/CSR) is a risk factor for increased mortality and morbidity in heart failure (HF). Adaptive servo‐ventilation (ASV) is a non‐invasive ventilationExpand
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Clinical outcome endpoints in heart failure trials: a European Society of Cardiology Heart Failure Association consensus document
Endpoint selection is a critically important step in clinical trial design. It poses major challenges for investigators, regulators, and study sponsors, and it also has important clinical andExpand
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Prevalence and Predictors of Sleep-Disordered Breathing in Patients With Stable Chronic Heart Failure: The SchlaHF Registry.
OBJECTIVES This prospective study investigated the prevalence of sleep-disordered breathing (SDB) and its predictors in patients with stable chronic heart failure (HF). BACKGROUND SDB isExpand
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Age- and gender-dependent adherence with continuous positive airway pressure therapy.
BACKGROUND Several studies have analysed adherence to continuous positive airway pressure (CPAP) therapy but little is known on the effects of age and gender. METHODS Data from 4281 patients withExpand
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Mechanisms underlying increased mortality risk in patients with heart failure and reduced ejection fraction randomly assigned to adaptive servoventilation in the SERVE-HF study: results of a
BACKGROUND A large randomised treatment trial (SERVE-HF) showed that treatment of central sleep apnoea with adaptive servoventilation in patients with heart failure and reduced ejection fractionExpand
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Management of continuous positive airway pressure treatment compliance using telemonitoring in obstructive sleep apnoea
Continuous positive airway pressure (CPAP) is an effective treatment for obstructive sleep apnoea (OSA), but treatment compliance is often unsatisfactory. This study investigated the efficacy andExpand
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Cardiovascular Outcomes With Minute Ventilation-Targeted Adaptive Servo-Ventilation Therapy in Heart Failure: The CAT-HF Trial.
BACKGROUND Sleep apnea is common in hospitalized heart failure (HF) patients and is associated with increased morbidity and mortality. OBJECTIVES The CAT-HF (Cardiovascular Improvements With MV-ASVExpand
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Pulmonary Hemodynamics in Obstructive Sleep Apnea: Frequency and Causes of Pulmonary Hypertension
The association between nocturnal apneas and transient pulmonary hypertension (PHT) has been well documented. However, there is controversy over the frequency and pathophysiological mechanisms ofExpand
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