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A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease
TLDR
This work estimated deaths and disability-adjusted life years (DALYs) attributable to the independent effects of 67 risk factors and clusters of risk factors for 21 regions in 1990 and 2010 and calculated the burden attributable to each risk factor exposure compared with the theoretical-minimum-risk exposure. Expand
Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
TLDR
The results for 1990 and 2010 supersede all previously published Global Burden of Disease results and highlight the importance of understanding local burden of disease and setting goals and targets for the post-2015 agenda taking such patterns into account. Expand
Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010
TLDR
The findings show the striking and growing challenge that these disorders pose for health systems in developed and developing regions. Expand
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
TLDR
Prevalence and severity of health loss were weakly correlated and age-specific prevalence of YLDs increased with age in all regions and has decreased slightly from 1990 to 2010, but population growth and ageing have increased YLD numbers and crude rates over the past two decades. Expand
Burden of Depressive Disorders by Country, Sex, Age, and Year: Findings from the Global Burden of Disease Study 2010
TLDR
The authors present severity proportions; burden by country, region, age, sex, and year; as well as burden of depressive disorders as a risk factor for suicide and ischemic heart disease. Expand
Resources for mental health: scarcity, inequity, and inefficiency
TLDR
Scarcity of available resources, inequities in their distribution, and inefficiencies in their use pose the three main obstacles to better mental health, especially in low-income and middle-income countries. Expand
Global variation in the prevalence and incidence of major depressive disorder: a systematic review of the epidemiological literature
TLDR
The findings provide a comprehensive and up-to-date profile of the prevalence of MDD globally and explore sources of heterogeneity in prevalence and guide the stratification of data in a meta-analysis. Expand
Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990–2013: quantifying the epidemiological
TLDR
Patterns of the epidemiological transition with a composite indicator of sociodemographic status, which was constructed from income per person, average years of schooling after age 15 years, and the total fertility rate and mean age of the population, were quantified. Expand
Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
TLDR
Ageing of the world's population is increasing the number of people living with sequelae of diseases and injuries, and a summary indicator that combines measures of income per capita, educational attainment, and fertility (the Socio-demographic Index) is created and used to compare observed patterns of health loss to the expected pattern for countries or locations with similar SDI scores. Expand
Global prevalence of anxiety disorders: a systematic review and meta-regression
TLDR
Anxiety disorders are common and the substantive and methodological factors identified here explain much of the variability in prevalence estimates, and specific attention should be paid to cultural differences in responses to survey instruments for anxiety disorders. Expand
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