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The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C
The target of rapamycin (TOR), as part of the rapamycin‐sensitive TOR complex 1 (TORC1), regulates various aspects of protein synthesis. Whether TOR functions in this process as part of TORC2 remains… Expand
Nucleotide-dependent Domain Movement in the ATPase Domain of a Human Type IIA DNA Topoisomerase*
- H. Wei, Alexander J. Ruthenburg, S. Bechis, G. Verdine
- Materials Science, Medicine
- Journal of Biological Chemistry
- 4 November 2005
Type IIA DNA topoisomerases play multiple essential roles in the management of higher-order DNA structure, including modulation of topological state, chromosome segregation, and chromatin… Expand
Targeted genomic sequencing identifies PRRT2 mutations as a cause of paroxysmal kinesigenic choreoathetosis
Background Paroxysmal kinesigenic choreoathetosis (PKC) is characterised by recurrent and brief attacks of involuntary movement, inherited as an autosomal dominant trait with incomplete penetrance. A… Expand
Ethanol production in syngas-fermenting Clostridium ljungdahlii is controlled by thermodynamics rather than by enzyme expression
Acetogenic bacteria are attracting interest as biocatalysts in the biotechnology industry, since they are able to ferment carbon monoxide (CO)-rich gases. Wild-type strains produce mainly acetate and… Expand
Comparisons of the biodistribution and toxicological examinations after repeated intravenous administration of silver and gold nanoparticles in mice
- L. Yang, Huijuan Kuang, W. Zhang, Zoraida P. Aguilar, H. Wei, H. Xu
- Chemistry, Medicine
- Scientific Reports
- 12 June 2017
Nanoparticles (NPs) size, surface functionalization, and concentration were claimed to contribute to distribution and toxicity outcomes of NPs in vivo. However, intrinsic chemical compositions of NPs… Expand
Size dependent biodistribution and toxicokinetics of iron oxide magnetic nanoparticles in mice.
In spite of the immense benefits from iron oxide magnetic nanoparticles (IOMNs), there is scanty information regarding their metabolic activities and toxicity in vivo. In this study, we investigated… Expand
Implant prostheses and adjacent tooth migration: preliminary retrospective survey using 3-dimensional occlusal analysis.
- H. Wei, Y. Tomotake, K. Nagao, T. Ichikawa
- The International journal of prosthodontics
- 1 July 2008
Occlusal force analysis was retrospectively evaluated to clarify the proximal contact loss after fixed implant prosthesis placement. Twenty-eight patients (55 prostheses) with fixed implant… Expand
Circadian Evening Complex Represses Jasmonate-Induced Leaf Senescence in Arabidopsis.
Plants initiate leaf senescence to reallocate energy and nutrients from aging to developing tissues for optimizing growth fitness and reproduction at the end of the growing season or under stress.… Expand
Bypasses in intracellular glucose metabolism in iron‐limited Pseudomonas putida
Decreased biomass growth in iron (Fe)‐limited Pseudomonas is generally attributed to downregulated expression of Fe‐requiring proteins accompanied by an increase in siderophore biosynthesis. Here, we… Expand
Novel strategies to enhance lateral flow immunoassay sensitivity for detecting foodborne pathogens.
- S. Shan, W. Lai, Y. Xiong, H. Wei, H. Xu
- Computer Science, Medicine
- Journal of agricultural and food chemistry
- 13 January 2015
This review presents the format and principle of lateral flow immunoassay strip and the development of conventional lateral flow ImmunoASSay for detecting foodborne pathogens. Expand