• Publications
  • Influence
Comparative Analysis of Period Genes in Teleost Fish Genomes
  • H. Wang
  • Biology, Medicine
  • Journal of Molecular Evolution
  • 6 June 2008
Period (Per) is a canonical circadian clock gene. The fruit fly, an invertebrate, has one per gene, while the human, a tetrapod vertebrate, has three Per genes. Per1, Per2, and Per3 of the tetrapodsExpand
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Molecular cloning and characterization of a novel member of the UDP‐GalNAc:polypeptide N‐acetylgalactosaminyltransferase family, pp‐GalNAc‐T12 1
We cloned in silico a novel human UDP‐GalNAc:polypeptide N‐acetylgalactosaminyltransferase (pp‐GalNAc‐T), pp‐GalNAc‐T12. The deduced amino acid sequence of pp‐GalNAc‐T12 contains all conserved motifsExpand
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Comparative analysis of teleost fish genomes reveals preservation of different ancient clock duplicates in different fishes.
  • H. Wang
  • Biology, Medicine
  • Marine genomics
  • 1 June 2008
Clock (Circadian locomotor output cycle kaput) was the first vertebrate circadian clock gene identified in a mouse forward genetics mutagenesis screen. It encodes a bHLH-PAS protein that is highlyExpand
  • 48
  • 3
Comparative genomic analysis of teleost fish bmal genes
  • H. Wang
  • Biology, Medicine
  • Genetica
  • 1 May 2009
Bmal1 (Brain and muscle ARNTlike 1) gene is a key circadian clock gene. Tetrapods also have the second Bmal gene, Bmal2. Fruit fly has only one bmal1/cycle gene. Interrogation of the five teleostExpand
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  • 3
A zebrafish model for hepatoerythropoietic porphyria
Defects in the enzymes involved in the haem biosynthetic pathway can lead to a group of human diseases known as the porphyrias. yquem (yqe tp61) is a zebrafish mutant with a photosensitive porphyriaExpand
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Identification and characterization of zebrafish ocular formation genes.
To study genes that are specifically expressed in the eyes, we employed microarray and in situ hybridization analyses to identify and characterize differentially expressed ocular genes in eyelessExpand
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Heme Regulates Exocrine Peptidase Precursor Genes in Zebrafish
We previously determined that yquem harbors a mutation in the gene encoding uroporphyrinogen decarboxylase (UROD), the fifth enzyme in heme biosynthesis, and established zebrafish yquem (yqe tp61 )Expand
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Isolation and expression of zebrafish zinc-finger transcription factor gene tsh1.
We report the expression patterns of tsh1, a zebrafish homologue of the Drosophila homeotic gene teashirt. Expression of tsh1 is first detected at the 2-somite stage (10h post-fertilization, hpf) atExpand
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Characterization of a novel human UDP-GalNAc transferase, pp-GalNAc-T10.
A novel member of the human UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (pp-GalNAc-T) gene family was cloned as a homolog of human pp-GalNAc-T7, and designatedExpand
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Zebrafish yolk‐specific not really started (nrs) gene is a vertebrate homolog of the Drosophila spinster gene and is essential for embryogenesis
By using retroviral insertional mutagenesis in zebrafish, we have identified a recessive lethal mutation in the not really started (nrs) gene. The nrs mutation disrupts a gene located in linkageExpand
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