• Publications
  • Influence
Evolutionary analyses of the human genome
The completion of the human genome will greatly accelerate the development of a new branch of science—evolutionary genomics. We can now directly address important questions about the evolutionaryExpand
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Left behind: widening disparities for males and females in US county life expectancy, 1985–2010
BackgroundThe United States spends more than any other country on health care. The poor relative performance of the US compared to other high-income countries has attracted attention and raisedExpand
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Forecasting United States mortality using cohort smoking histories
  • H. Wang, S. Preston
  • Medicine
  • Proceedings of the National Academy of Sciences
  • 13 January 2009
In this paper, we introduce a recently established relationship between cohort smoking patterns and adult mortality into mortality projections for the United States. In particular, we incorporate aExpand
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InSite: a computational method for identifying protein-protein interaction binding sites on a proteome-wide scale
We propose InSite, a computational method that integrates high-throughput protein and sequence data to infer the specific binding regions of interacting protein pairs. We compared our predictionsExpand
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A Protein Domain-Based Interactome Network for C. elegans Early Embryogenesis
Many protein-protein interactions are mediated through independently folding modular domains. Proteome-wide efforts to model protein-protein interaction or "interactome" networks have largely ignoredExpand
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Mapping Plasmodium falciparum Mortality in Africa between 1990 and 2015.
BACKGROUND Malaria control has not been routinely informed by the assessment of subnational variation in malaria deaths. We combined data from the Malaria Atlas Project and the Global Burden ofExpand
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Mapping under-5 and neonatal mortality in Africa, 2000–15: a baseline analysis for the Sustainable Development Goals
Summary Background During the Millennium Development Goal (MDG) era, many countries in Africa achieved marked reductions in under-5 and neonatal mortality. Yet the pace of progress toward these goalsExpand
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The expression and significance of survivin mRNA in urinary bladder carcinomas
Objective To investigate the practicability of survivin detection in urine as a novel diagnostic method and prognostic molecular marker of bladder cancer.Methods Nested RT-PCR was used to detectExpand
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Identification and characterization of microRNAs in white and brown alpaca skin
BackgroundMicroRNAs (miRNAs) are small, non-coding 21–25 nt RNA molecules that play an important role in regulating gene expression. Little is known about the expression profiles and functions ofExpand
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Estimation of district-level under-5 mortality in Zambia using birth history data, 1980-2010.
Birth history data-the primary source of data on under-5 mortality in developing countries-are infrequently used for subnational estimates due to concerns over small sample sizes. In this study weExpand
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