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Molecular cues to implantation.
Successful implantation is the result of reciprocal interactions between the implantation-competent blastocyst and receptive uterus. Although various cellular aspects and molecular pathways of thisExpand
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Roadmap to embryo implantation: clues from mouse models
  • H. Wang, S. Dey
  • Biology, Medicine
  • Nature Reviews Genetics
  • 1 March 2006
Implantation involves an intricate discourse between the embryo and uterus and is a gateway to further embryonic development. Synchronizing embryonic development until the blastocyst stage with theExpand
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Ionotropic and Metabotropic Receptors, Protein Kinase A, Protein Kinase C, and Src Contribute to C-Fiber-Induced ERK Activation and cAMP Response Element-Binding Protein Phosphorylation in Dorsal
Molecular mechanisms underlying C-fiber stimulation-induced ERK (extracellular signal-regulated kinase) activation in dorsal horn neurons and its contribution to central sensitization have beenExpand
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Physiological and molecular determinants of embryo implantation.
Embryo implantation involves the intimate interaction between an implantation-competent blastocyst and a receptive uterus, which occurs in a limited time period known as the window of implantation.Expand
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Nociceptors Are Interleukin-1β Sensors
A cardinal feature of inflammation is heightened pain sensitivity at the site of the inflamed tissue. This results from the local release by immune and injured cells of nociceptor sensitizers,Expand
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The Voltage-Gated Sodium Channel Nav1.9 Is an Effector of Peripheral Inflammatory Pain Hypersensitivity
We used a mouse with deletion of exons 4, 5, and 6 of the SCN11A (sodium channel, voltage-gated, type XI, α) gene that encodes the voltage-gated sodium channel Nav1.9 to assess its contribution toExpand
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Jekyll and hyde: two faces of cannabinoid signaling in male and female fertility.
Mammalian reproduction is a complicated process designed to diversify and strengthen the genetic complement of the offspring and to safeguard regulatory systems at various steps for propagatingExpand
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Crosstalk between peroxisome proliferator-activated receptor δ and VEGF stimulates cancer progression
  • D. Wang, H. Wang, +6 authors R. Dubois
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 12 December 2006
Peroxisome proliferator-activated receptor (PPAR) δ is a member of the nuclear hormone receptor superfamily. PPARδ may ameliorate metabolic diseases such as obesity and diabetes. However, PPARδ'sExpand
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CXCL1 induced by prostaglandin E2 promotes angiogenesis in colorectal cancer
Chronic inflammation is a well-known risk factor for cancer. Proinflammatory mediators such as prostaglandin E2 (PGE2) promote colorectal tumor growth by stimulating angiogenesis, cell invasion, andExpand
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Global gene expression analysis identifies molecular pathways distinguishing blastocyst dormancy and activation.
Delayed implantation (embryonic diapause) occurs when the embryo at the blastocyst stage achieves a state of suspended animation. During this period, blastocyst growth is very slow, with minimal orExpand
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