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Gankyrin drives malignant transformation of chronic liver damage-mediated fibrosis via the Rac1/JNK pathway
TLDR
Gankyrin promotes liver fibrosis/cirrhosis progression into hepatocarcinoma relying on a persistent liver injury and inflammatory microenvironment, and the combined inhibition of ganksyrin and Rac1/JNK as a potential prevention mechanism for cirrhosis transition is suggested. Expand
[Non-invasive fibrosis indexes in predicting acute liver function deterioration after transcatheter arterial chemoembolization].
TLDR
Comparing to Child-Pugh score, APRI and FIB-4 score have similar accuracy but better NPV and sensitivity in predicting post-TACE ALFD and thereafter they are good for selection of low-risk patients for TACE treatment. Expand
The targeted inhibitory effects of human amniotic fluid stem cells carrying CXCR4 promoter and DAL-1 on non-small cell lung carcinoma growth
TLDR
It is found that infection of Ad-CXCR4-DAL-1 increased the apoptosis of A549 NSCLC cells but not 16HBE normal human bronchial epithelial cells, and hAFS cells are capable of carrying adenovirus vectors, specifically targeting to lung cancer, and causing oncolytic effects when administered in vivo. Expand
A case of lues maligna in an AIDS patient
TLDR
Although the clinical manifestations of lues maligna are complicated and severe, the response to the therapy of penicillin is excellent and the important association between luesmaligna and HIV/AIDS is shown. Expand
Influence of Adrenal Glands on the Modulation of Prolactin Gene Expression by the Endogenous Benzodiazepine Ligand Octadecaneuropeptide in the Male Rat Pituitary Gland
TLDR
Data indicate that an endogenous neuropeptide interacting with the GABAA receptor complex can stimulate prolactin gene expression and suggest that the adrenal glands may produce factor(s) capable of decreasing Prolactin mRNA. Expand
[Role of apoptosis and bcl-2 gene in the temporomandibular joint development].
TLDR
Apoptosis regulated by bcl-2 plays an important role in prenatal and postnatal development of TMJ and the cells of apoptosis mainly located in the proliferative zone and the area between the prehypertrophic Zone and the late hypertrophic zone. Expand
[The role of bcl-2 and bax genes and programmed cell death in the temporomandibular joint development].
  • S. Li, Y. Jin, H. Wang
  • Biology, Medicine
  • Zhonghua kou qiang yi xue za zhi = Zhonghua…
  • 1 July 2000
TLDR
PCD of condylar cartilage is regulated by bcl-2 and bax gene, the number and site of PCD are attributed to the change of bcl1 and bx gene, and b cl-2 is an important gene in maintaining survival of chondrocytes during the proliferation, differentiation and maturation. Expand
MicroRNA‐4443 regulates monocyte activation by targeting tumor necrosis factor receptor associated factor 4 in stroke‐induced immunosuppression
TLDR
The purpose of this study was to investigate the expression patterns of miRNAs in peripheral blood mononuclear cells from AIS patients and further explore related molecular mechanisms in stroke‐induced immunodeficiency syndrome (SIDS). Expand
Selenium minerals and the recovery of selenium from copper refinery anode slimes
laboratory (Greenwood et al., 1984). The discovery of selenium was made by the Swedish chemist J.J. Berzelius and J.G. Gahn, who isolated selenium from a red residue in sulphuric acid from pyriteExpand
[A family of tumor necrosis factor receptor-associated periodic syndrome].
TLDR
TRAPS is characterized by periodic fever,arthralgia,myalgia, multiple serositis,periorbital edema and migratory cutaneous rash, with a significant decrease in plasma level of TNFR1 and NK cells, and a pathogenic variation in TNFRSF1A gene is revealed. Expand
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